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一个移动的目标:我们如何定义回避/限制型食物摄入障碍可以使它的患病率增加一倍。

A Moving Target: How We Define Avoidant/Restrictive Food Intake Disorder Can Double Its Prevalence.

机构信息

Neuroendocrine Unit, Massachusetts General Hospital, Boston, Massachusetts.

Eating Disorders Clinical and Research Program, Massachusetts General Hospital, Boston, Massachusetts.

出版信息

J Clin Psychiatry. 2021 Sep 7;82(5):20m13831. doi: 10.4088/JCP.20m13831.

Abstract

The criteria for avoidant/restrictive food intake disorder (ARFID) include ambiguities. Diagnostic criteria that allow for clinical judgment are essential for clinical practice. However, ambiguities can have major implications for treatment access and comparability and generalizability of research studies. The purpose of this study was to determine the degree to which distinct operationalizations of the diagnostic criteria for ARFID contribute to differences in the frequency of individuals who are eligible for the ARFID diagnosis. Because criteria B, C, and D are rule-outs, we focused on criterion A, identified 19 potential operational definitions, and determined the extent to which these different methods impacted the proportion of individuals who met criteria for ARFID in a sample of children, adolescents, and young adults (n = 80; September 2016-February 2020) enrolled in an avoidant/restrictive eating study. Within each criterion, the proportion of individuals meeting diagnostic criteria differed significantly across the methodologies (all values < .008). Using the strictest definition of each criterion, 50.0% (n = 40) of participants met criteria for ARFID. In contrast, under the most lenient definition of each criterion, the number nearly doubled, resulting in 97.5% (n = 78) meeting ARFID criteria. Comparison of diagnostic definitions for ARFID among children, adolescents, and young adults confirmed a broad range of statistically distinct proportions within a single sample. Our findings support the need for additional contextual support and consensus among disciplines on operationalization in both research and clinical settings.

摘要

回避/限制型进食障碍(ARFID)的诊断标准存在一些模糊之处。允许临床判断的诊断标准对于临床实践至关重要。然而,这些模糊之处可能会对治疗的可及性以及研究的可比性和普遍性产生重大影响。本研究的目的是确定 ARFID 诊断标准的不同操作化方式在符合 ARFID 诊断的个体频率上的差异程度。

由于标准 B、C 和 D 是排除标准,我们专注于标准 A,确定了 19 种潜在的操作定义,并确定了这些不同方法在一个纳入回避/限制进食研究的儿童、青少年和年轻成年人样本(n = 80;2016 年 9 月至 2020 年 2 月)中对符合 ARFID 标准的个体比例的影响程度。在每个标准内,符合诊断标准的个体比例在不同方法之间存在显著差异(所有 值 <.008)。使用每个标准的最严格定义,50.0%(n = 40)的参与者符合 ARFID 标准。相比之下,在每个标准的最宽松定义下,符合 ARFID 标准的人数几乎翻了一番,达到 97.5%(n = 78)。

对儿童、青少年和年轻成年人的 ARFID 诊断定义进行比较,证实了在单个样本中存在广泛的统计上不同的比例。我们的研究结果支持在研究和临床环境中,需要在操作化方面为不同学科提供额外的背景支持和共识。

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