Miyashita Mariko, Ito Narushi, Ikeda Satoshi, Murayama Tatsuro, Oguma Koji, Kimura Jun
TANITA Corporation, Itabashi-ku, Tokyo 174-8630, Japan.
Biosens Bioelectron. 2009 Jan 1;24(5):1336-40. doi: 10.1016/j.bios.2008.07.072. Epub 2008 Aug 13.
The highly sensitive urine glucose meter based on amperometric glucose sensor was developed and commercialized. It shows remarkable performances of wide measurement range in 0-2000 mgdl(-1), rapid response time as 6s and robustness against influence by interferents like ascorbic acid or acetaminophen. Correlation between the developed urine glucose meter and commercialized clinical-use urine glucose analyzer showed excellent linear relationship. The monitoring of postmeal blood glucose levels by assess of urine glucose of actual subjects was performed with the developed urine glucose meter. The experimental results suggest the urine glucose level 120 min following the meal should be the appropriate index for diabetes or impaired glucose tolerance to control blood glucose level. The new portable meter was developed, and is expected for flexible use at places other than home or office.
基于安培型葡萄糖传感器的高灵敏度血糖仪已研发并实现商业化。它在0 - 2000 mg/dl(-1)范围内具有宽测量范围、6秒快速响应时间以及对抗坏血酸或对乙酰氨基酚等干扰物影响的稳健性等显著性能。所研发的血糖仪与商业化临床用尿糖分析仪之间的相关性显示出良好的线性关系。使用所研发的血糖仪对实际受试者的尿糖进行评估以监测餐后血糖水平。实验结果表明，餐后120分钟的尿糖水平应是控制血糖水平的糖尿病或糖耐量受损的合适指标。新型便携式血糖仪已研发成功，有望在家庭或办公室以外的场所灵活使用。
