Segura Sonia, Requena Luis
Department of Dermatology, Hospital del Mar, IMAS, Passeig Marítim 25-29, 08003 Barcelona, Spain.
Dermatol Clin. 2008 Oct;26(4):419-24, v. doi: 10.1016/j.det.2008.05.011.
The panniculitides comprise a group of heterogeneous inflammatory diseases that involve the subcutaneous fat. Histopathologic study is required for the specific diagnosis of these disorders, because different panniculitides usually show the same clinical appearance, which consists of erythematous nodules on the lower extremities. The histopathologic study of panniculitis is difficult, however, because of an inadequate clinicopathologic correlation and the changing evolutive nature of the lesions. Some cutaneous lymphomas may simulate panniculitis, both from clinical and histopathologic points of view, and for that reason are included in this article despite the fact that they are not inflammatory processes but authentic lymphocytic neoplasms involving subcutaneous tissue.
脂膜炎是一组累及皮下脂肪的异质性炎症性疾病。这些疾病的特异性诊断需要进行组织病理学研究，因为不同类型的脂膜炎通常具有相同的临床表现，即下肢出现红斑性结节。然而，由于临床病理相关性不足以及病变不断演变的性质，脂膜炎的组织病理学研究存在困难。从临床和组织病理学角度来看，一些皮肤淋巴瘤可能酷似脂膜炎，因此尽管它们并非炎症性疾病，而是累及皮下组织的真正淋巴细胞性肿瘤，但本文仍将其纳入讨论。
