头颈癌：一种不断演变的治疗模式。
Head and neck cancer: an evolving treatment paradigm.
作者信息
Cognetti David M, Weber Randal S, Lai Stephen Y
机构信息
Department of Otolaryngology, University of Pittsburgh Medical Center, Pittsburgh, PA, USA.
出版信息
Cancer. 2008 Oct 1;113(7 Suppl):1911-32. doi: 10.1002/cncr.23654.
Abstract
Since the inception of this journal in 1948, the understanding of etiologic factors that contribute to and the treatment of head and neck cancer has evolved dramatically. Advances in surgery, radiation therapy, and chemotherapy have improved locoregional control, survival, and quality of life. The outcomes of these treatment modalities have shifted the focus of curative efforts from radical ablation to preservation and restoration of function. This evolution has been documented in the pages of Cancer for the past 6 decades. This review focuses on the evolution of treatment approaches for head and neck cancer and future directions while recognizing the historic contributions recorded within this journal.
摘要
自本期刊于1948年创刊以来，对头颈部癌症致病因素的认识以及治疗方法都发生了巨大的演变。手术、放射治疗和化学疗法的进展改善了局部区域控制、生存率和生活质量。这些治疗方式的成果已将治愈努力的重点从根治性切除转移至功能的保留和恢复。在过去60年里，《癌症》期刊的各期都记录了这一演变过程。本综述着重探讨头颈部癌症治疗方法的演变及未来方向，同时铭记本期刊所记载的历史性贡献。
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