Zupancic Melanie, Annamalai Ani, Brenneman Jennifer, Ranatunga Sriya
Department of Internal Medicine, Division of Internal Medicine/Psychiatry, Southern Illinois University School of Medicine, Springfield, IL 62794, USA.
J Gen Intern Med. 2008 Dec;23(12):2136-9. doi: 10.1007/s11606-008-0794-7. Epub 2008 Sep 23.
Carcinomatous polyarthritis (CP) is a rare paraneoplastic disorder that has been associated with a variety of solid tumors. It presents in a similar manner to other polyarticular disorders and often precedes detection of the underlying malignancy, making recognition critical. CP responds to the treatment of the neoplastic process. We present a patient who initially presented with asymmetric inflammatory polyarthritis who was later diagnosed with bronchogenic carcinoma. Following the case report we present our learning objectives, which include the differential diagnosis of inflammatory polyarthritis, diagnostic approach to CP, and features that distinguish it from other more common causes of polyarthritis. We conclude with a brief discussion of the pathophysiology and management of CP.
癌性多关节炎(CP)是一种罕见的副肿瘤性疾病,与多种实体瘤相关。它的表现与其他多关节疾病相似,且常在潜在恶性肿瘤被发现之前出现,因此识别至关重要。CP对肿瘤性病变的治疗有反应。我们报告一名最初表现为不对称性炎性多关节炎,后来被诊断为支气管源性癌的患者。在病例报告之后,我们提出了学习目标,包括炎性多关节炎的鉴别诊断、CP的诊断方法以及将其与其他更常见的多关节炎病因相区别的特征。我们最后简要讨论了CP的病理生理学和管理。