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口腔寻常型天疱疮:71例临床分析

Pemphigus vulgaris in oral cavity: clinical analysis of 71 cases.

作者信息

Shamim Thorakkal, Varghese Vengal Ipe, Shameena Pallikandi Maliyekkal, Sudha Sivasankar

机构信息

Department of Oral Pathology and Microbiology. Educare Institute of Dental Sciences. Chattiparamba. India.

出版信息

Med Oral Patol Oral Cir Bucal. 2008 Oct 1;13(10):E622-6.

PMID:18830168
Abstract

OBJECTIVE

The purpose of the study was to evaluate the clinical presentation of pemphigus vulgaris in the oral cavity.

STUDY DESIGN

A retrospective study of 71 cases of pemphigus vulgaris obtained over a period of 7 years from 1st January 2001 to 31st December 2007 in the Department of Oral Pathology, Government Dental College and Department of Dermatology, Government Medical College, Calicut was designed. Clinical details such as age, sex, intraoral distribution, extent of oral lesions, oral presentation, duration, oral involvement (whether primary or secondary) and mode of onset were noted from the files of corresponding Departments.

RESULTS

In about 53.52% of cases, the oral cavity was the primary site of involvement. The mean age was 42.73 years and male: female ratio was 1:1.73. The most commonly affected sites were the buccal mucosa and the palate. The disease began with generalized lesions rather than localized lesions. All cases presented as ulcers or erosions.

CONCLUSION

Although minor differences were noted, the results of this study are in relatively good agreement with the literature with regard to the age, gender, and initial presentation of pemphigus vulgaris.

摘要

目的

本研究旨在评估寻常型天疱疮在口腔中的临床表现。

研究设计

对2001年1月1日至2007年12月31日这7年间在政府牙科学院口腔病理科以及卡利卡特政府医学院皮肤科获取的71例寻常型天疱疮病例进行回顾性研究。从相应科室的档案中记录年龄、性别、口腔内分布、口腔病变范围、口腔表现、病程、口腔受累情况(原发性或继发性)以及发病方式等临床细节。

结果

约53.52%的病例中,口腔是受累的主要部位。平均年龄为42.73岁,男女比例为1:1.73。最常受累的部位是颊黏膜和腭部。疾病始于全身性病变而非局限性病变。所有病例均表现为溃疡或糜烂。

结论

尽管存在一些细微差异,但本研究在寻常型天疱疮的年龄、性别和初始表现方面的结果与文献相对较为一致。

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