Vegas Bustamante Erika, Gargallo Albiol Jordi, Berini Aytés Leonardo, Gay Escoda Cosme
Implantology, University of Barcelona Dental School, Barcelona, Spain.
Med Oral Patol Oral Cir Bucal. 2008 Oct 1;13(10):E653-6.
A study is made of the principal characteristics of the oral lesions biopsied in our Service of Oral Surgery and histologically diagnosed as corresponding to fibro-osseous lesions of the maxillas.
A retrospective review was made of all the biopsies made in a Service of Oral Surgery between 1996 and 2003. The reason for consultation was analyzed, along with patient age, sex, clinical and radiological characteristics, tentative diagnosis, histological diagnosis and treatment provided.
A total of 1238 biopsies were performed during the study period. Of these, only 11 corresponded to benign fibro-osseous lesions (7 women and 4 men). The mean patient age was 44 years (range 19-72 years). The most frequent location was the mandible (8 of the cases). In 7 patients the lesions constituted casual radiological findings; 4 presented bulging of the vestibular cortical bone, though only one of them reported pain. The histological diagnoses comprised 7 cemento-ossifying fibromas and 4 fibrous dysplasias. In 9 cases surgical resection was carried out, while in one case an incisional biopsy was performed, and in the remaining case curettage was decided.
These lesions are more frequent in women than in men, and the age at presentation is variable. In terms of lesion location, fibrous dysplasia is more common in the upper maxilla, while cemento-ossifying fibroma is more frequently found in the mandible. The diagnosis of such lesions is established upon contrasting the data obtained from the anamnesis, physical examination, the radiological characteristics, the intraoperative findings and the histological study, since both disorders have similar clinical and histological features--despite the fact that they constitute distinct disease conditions.
对我们口腔外科活检的口腔病变的主要特征进行了研究,这些病变经组织学诊断为上颌骨的纤维-骨病变。
对1996年至2003年间在某口腔外科进行的所有活检进行回顾性研究。分析了会诊原因、患者年龄、性别、临床和放射学特征、初步诊断、组织学诊断及所提供的治疗。
在研究期间共进行了1238例活检。其中,仅11例为良性纤维-骨病变(7名女性和4名男性)。患者平均年龄为44岁(范围19 - 72岁)。最常见的部位是下颌骨(8例)。7例患者的病变为偶然的放射学发现;4例出现前庭皮质骨膨隆,其中仅1例报告有疼痛。组织学诊断包括7例骨化纤维瘤和4例骨纤维异常增殖症。9例进行了手术切除,1例进行了切开活检,其余1例决定刮除术。
这些病变在女性中比在男性中更常见,发病年龄各不相同。就病变部位而言,骨纤维异常增殖症在上颌骨更常见,而骨化纤维瘤在下颌骨更常见。此类病变的诊断是通过对比从病史、体格检查、放射学特征、术中发现及组织学研究获得的数据来确立的,因为这两种疾病具有相似的临床和组织学特征——尽管它们是不同的疾病状况。