Nishidate Izumi, Sasaoka Kiyohiro, Yuasa Testuya, Niizeki Kyuichi, Maeda Takaaki, Aizu Yoshihisa
Graduate School of Bio-Applications and Systems Engineering, Tokyo University of Agriculture and Technology, Tokyo, Japan.
Opt Lett. 2008 Oct 1;33(19):2263-5. doi: 10.1364/ol.33.002263.
A method is proposed for visualizing simply the concentrations of melanin, oxygenated blood, and deoxygenated blood in skin tissue using digital RGB images. The total blood concentration and oxygen saturation can also be reconstructed. Monte Carlo simulation of light transport specifies a relation between the chromophore concentrations and Commission Internationale de l'Eclairage XYZ, which are compatible with the common RGB working space. Experiments with a tissuelike agar gel phantom demonstrated the possibility of the method. In vivo imaging of a human hand during forearm occlusion demonstrated the ability of the method to evaluate hemodynamics of skin tissue.
提出了一种利用数字RGB图像简单可视化皮肤组织中黑色素、氧合血和脱氧血浓度的方法。还可以重建全血浓度和血氧饱和度。光传输的蒙特卡罗模拟确定了发色团浓度与国际照明委员会XYZ之间的关系，这与常见的RGB工作空间兼容。使用组织样琼脂凝胶体模进行的实验证明了该方法的可行性。在前臂闭塞期间对人手进行的体内成像证明了该方法评估皮肤组织血流动力学的能力。
