银杏外种皮中羟基链烯基水杨酸对耐万古霉素肠球菌的抗菌活性
Antibacterial activity of hydroxyalkenyl salicylic acids from sarcotesta of Ginkgo biloba against vancomycin-resistant Enterococcus.
作者信息
Choi J G, Jeong S I, Ku C S, Sathishkumar M, Lee J J, Mun S P, Kim S M
机构信息
National Agricultural Products Quality Management Service, Ministry of Agriculture and Forestry, Jeonju 561-823, South Korea.
出版信息
Fitoterapia. 2009 Jan;80(1):18-20. doi: 10.1016/j.fitote.2008.09.001. Epub 2008 Sep 11.
A chloroform fraction prepared from the sarcotesta of Ginkgo biloba showed potent inhibitory activity against vancomycin-resistant Enterococcus (VRE). The active compounds were elucidated to be 2-hydroxy-6-(8-pentadecenyl) salicylic acid (1) and 2-hydroxy-6-(10-heptadecenyl) salicylic acid (2) based on their spectral analysis. Compounds 1 and 2 showed significant antibacterial activities against VRE.
从银杏外种皮制备的氯仿提取物对耐万古霉素肠球菌（VRE）显示出强效抑制活性。基于光谱分析，确定活性化合物为2-羟基-6-（8-十五碳烯基）水杨酸（1）和2-羟基-6-（10-十七碳烯基）水杨酸（2）。化合物1和2对VRE显示出显著的抗菌活性。
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