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神经康复中的脑机接口

Brain-computer interfaces in neurological rehabilitation.

作者信息

Daly Janis J, Wolpaw Jonathan R

机构信息

Cognitive and Motor Learning Laboratory, Louis Stokes Cleveland VA Medical Center, Cleveland, OH 44106, USA.

出版信息

Lancet Neurol. 2008 Nov;7(11):1032-43. doi: 10.1016/S1474-4422(08)70223-0. Epub 2008 Oct 2.

Abstract

Recent advances in analysis of brain signals, training patients to control these signals, and improved computing capabilities have enabled people with severe motor disabilities to use their brain signals for communication and control of objects in their environment, thereby bypassing their impaired neuromuscular system. Non-invasive, electroencephalogram (EEG)-based brain-computer interface (BCI) technologies can be used to control a computer cursor or a limb orthosis, for word processing and accessing the internet, and for other functions such as environmental control or entertainment. By re-establishing some independence, BCI technologies can substantially improve the lives of people with devastating neurological disorders such as advanced amyotrophic lateral sclerosis. BCI technology might also restore more effective motor control to people after stroke or other traumatic brain disorders by helping to guide activity-dependent brain plasticity by use of EEG brain signals to indicate to the patient the current state of brain activity and to enable the user to subsequently lower abnormal activity. Alternatively, by use of brain signals to supplement impaired muscle control, BCIs might increase the efficacy of a rehabilitation protocol and thus improve muscle control for the patient.

摘要

近年来,脑信号分析、训练患者控制这些信号以及计算能力的提升,使严重运动障碍患者能够利用脑信号进行交流并控制周围环境中的物体,从而绕过受损的神经肌肉系统。基于非侵入性脑电图(EEG)的脑机接口(BCI)技术可用于控制电脑光标或肢体矫形器、进行文字处理和访问互联网,以及实现环境控制或娱乐等其他功能。通过重新建立一定程度的独立性,BCI技术可显著改善患有诸如晚期肌萎缩侧索硬化症等严重神经系统疾病患者的生活。BCI技术还可能通过利用EEG脑信号帮助引导依赖活动的脑可塑性,向患者指示脑活动的当前状态并使使用者随后降低异常活动,从而使中风或其他创伤性脑疾病后的患者恢复更有效的运动控制。或者,通过利用脑信号补充受损的肌肉控制,BCI可能提高康复方案的疗效,进而改善患者的肌肉控制能力。

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