Guijarro Ricardo, Montes Julio, Sanromán Carlos, Monreal Manuel
Servicio de Medicina Interna, Hospital Universitario Carlos Haya de Málaga, Spain.
Eur J Intern Med. 2008 Oct;19(6):443-6. doi: 10.1016/j.ejim.2007.06.026. Epub 2008 Mar 4.
The aim of this study was to validate the baseline characteristics of the RIETE cohort against the much larger national Spanish population-based database.
The RIETE is an ongoing registry of consecutive patients with symptomatic, objectively confirmed, acute venous thromboembolism (VTE). We compared some baseline characteristics and death rates in the administrative database from the Spanish Ministry of Health (CMBD, Conjunto Mínimo Básico de Datos) with those in the RIETE registry.
During the study period, data on 87,733 patients with VTE were collected from the CMBD and 8053 from the RIETE. There were no differences between the groups in gender, mean age, clinical presentation of the VTE event, or the presence of recent surgery; however, chronic lung disease, chronic heart failure, and pregnancy were slightly more common in patients in the CMBD. There were no differences in mortality rate in patients with deep vein thrombosis, but the 12% death rate in patients with pulmonary embolism in the CMBD was three times higher than the 4.1% found in the RIETE. However, when only considering patients with pulmonary embolism who had objective tests, the 4.8% death rate in the CMBD no longer differed from the mortality in the RIETE.
Our data reveal that the information in the RIETE is very close to that observed in the CMBD, thus supporting the validity of the data in the RIETE.
本研究的目的是对照规模大得多的西班牙全国性基于人群的数据库，验证RIETE队列的基线特征。
RIETE是一个对有症状、经客观证实的急性静脉血栓栓塞症（VTE）连续患者的正在进行的登记系统。我们将西班牙卫生部行政数据库（CMBD，基本最小数据集）中的一些基线特征和死亡率与RIETE登记系统中的进行了比较。
在研究期间，从CMBD收集了87733例VTE患者的数据，从RIETE收集了8053例。两组在性别、平均年龄、VTE事件的临床表现或近期手术情况方面无差异；然而，慢性肺病、慢性心力衰竭和妊娠在CMBD患者中略为常见。深静脉血栓形成患者的死亡率无差异，但CMBD中肺栓塞患者12%的死亡率是RIETE中4.1%的三倍。然而，仅考虑进行了客观检查的肺栓塞患者时，CMBD中4.8%的死亡率与RIETE中的死亡率不再有差异。
我们的数据表明，RIETE中的信息与CMBD中观察到的信息非常接近，从而支持了RIETE中数据的有效性。
