Caputo R, Crosti C, Cainelli T
J Invest Dermatol. 1977 Feb;68(2):98-104. doi: 10.1111/1523-1747.ep12491647.
Intracytoplasmic granules with a unique and highly complex ultrastructure, have been observed within the cellular infiltrate of the lesions of two patients with papular histiocytosis. Examination of serial sections has enabled construction of a three-dimensional model of these granules, which appear to be composed of an elaborate arrangement of membranes and vesicles. Two hypotheses (endocytosis and exocytosis) are proposed for the mode of formation of these unique cytoplasmic structures.
在两名丘疹性组织细胞增多症患者病变的细胞浸润内观察到具有独特且高度复杂超微结构的胞质颗粒。对连续切片的检查使得能够构建这些颗粒的三维模型,这些颗粒似乎由精细排列的膜和囊泡组成。针对这些独特细胞质结构的形成方式提出了两种假说(内吞作用和外排作用)。