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New variable-number tandem-repeat markers for typing Mycobacterium avium subsp. paratuberculosis and M. avium strains: comparison with IS900 and IS1245 restriction fragment length polymorphism typing.用于鸟分枝杆菌副结核亚种和鸟分枝杆菌菌株分型的新型可变数目串联重复序列标记：与IS900和IS1245限制性片段长度多态性分型的比较
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本文引用的文献

1
Evaluation and strategy for use of MIRU-VNTRplus, a multifunctional database for online analysis of genotyping data and phylogenetic identification of Mycobacterium tuberculosis complex isolates.用于结核分枝杆菌复合群分离株基因分型数据在线分析和系统发育鉴定的多功能数据库MIRU-VNTRplus的评估与应用策略
J Clin Microbiol. 2008 Aug;46(8):2692-9. doi: 10.1128/JCM.00540-08. Epub 2008 Jun 11.
2
Mycobacterium avium subsp. paratuberculosis and M. avium subsp. avium are independently evolved pathogenic clones of a much broader group of M. avium organisms.副结核分枝杆菌鸟亚种和鸟分枝杆菌鸟亚种是鸟分枝杆菌这一更为广泛的菌群中独立进化的致病克隆。
J Bacteriol. 2008 Apr;190(7):2479-87. doi: 10.1128/JB.01691-07. Epub 2008 Feb 1.
3
Influence of type of culture medium on characterization of Mycobacterium avium subsp. paratuberculosis subtypes.培养基类型对副结核分枝杆菌亚种亚型特征的影响。
J Clin Microbiol. 2008 Jan;46(1):145-9. doi: 10.1128/JCM.01769-07. Epub 2007 Oct 24.
4
New variable-number tandem-repeat markers for typing Mycobacterium avium subsp. paratuberculosis and M. avium strains: comparison with IS900 and IS1245 restriction fragment length polymorphism typing.用于鸟分枝杆菌副结核亚种和鸟分枝杆菌菌株分型的新型可变数目串联重复序列标记：与IS900和IS1245限制性片段长度多态性分型的比较
J Clin Microbiol. 2007 Aug;45(8):2404-10. doi: 10.1128/JCM.00476-07. Epub 2007 May 30.
5
Proposal for standardization of optimized mycobacterial interspersed repetitive unit-variable-number tandem repeat typing of Mycobacterium tuberculosis.结核分枝杆菌优化的分枝杆菌插入重复单位-可变数目串联重复序列分型标准化方案。
J Clin Microbiol. 2006 Dec;44(12):4498-510. doi: 10.1128/JCM.01392-06. Epub 2006 Sep 27.
6
Short-sequence-repeat analysis of Mycobacterium avium subsp. paratuberculosis and Mycobacterium avium subsp. avium isolates collected from animals throughout the United States reveals both stability of loci and extensive diversity.对从美国各地动物身上分离出的副结核分枝杆菌亚种和鸟分枝杆菌亚种进行短串联重复序列分析，结果显示基因座既具有稳定性又具有广泛的多样性。
J Clin Microbiol. 2006 Aug;44(8):2970-3. doi: 10.1128/JCM.00584-06.
7
Current understanding of the genetic diversity of Mycobacterium avium subsp. paratuberculosis.当前对副结核分枝杆菌鸟分枝杆菌亚种遗传多样性的认识。
Microbes Infect. 2006 Apr;8(5):1406-18. doi: 10.1016/j.micinf.2005.12.003. Epub 2006 Jan 26.
8
Diversity of potential short tandem repeats in Mycobacterium leprae and application for molecular typing.麻风分枝杆菌中潜在短串联重复序列的多样性及其在分子分型中的应用
J Clin Microbiol. 2005 Oct;43(10):5221-9. doi: 10.1128/JCM.43.10.5221-5229.2005.
9
The complete genome sequence of Mycobacterium avium subspecies paratuberculosis.副结核分枝杆菌鸟分枝杆菌亚种的全基因组序列
Proc Natl Acad Sci U S A. 2005 Aug 30;102(35):12344-9. doi: 10.1073/pnas.0505662102. Epub 2005 Aug 22.
10
Genomic polymorphisms for Mycobacterium avium subsp. paratuberculosis diagnostics.用于副结核分枝杆菌诊断的基因组多态性
J Clin Microbiol. 2005 Aug;43(8):3704-12. doi: 10.1128/JCM.43.8.3704-3712.2005.

鸟分枝杆菌副结核亚种分离株的多位点短序列重复与分枝杆菌散布重复单位可变数目串联重复联合分型

Combined multilocus short-sequence-repeat and mycobacterial interspersed repetitive unit-variable-number tandem-repeat typing of Mycobacterium avium subsp. paratuberculosis isolates.

作者信息

Thibault Virginie C, Grayon Maggy, Boschiroli Maria Laura, Willery Eve, Allix-Béguec Caroline, Stevenson Karen, Biet Franck, Supply Philip

机构信息

INRA, UR1282, Infectiologie Animale, Santé Publique, Nouzilly, France.

出版信息

J Clin Microbiol. 2008 Dec;46(12):4091-4. doi: 10.1128/JCM.01349-08. Epub 2008 Oct 15.

DOI:10.1128/JCM.01349-08
PMID:18923016
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2593263/
Abstract

Short-sequence-repeat (SSR) sequencing was applied to 127 Mycobacterium avium subsp. paratuberculosis isolates typed by mycobacterial interspersed repetitive unit-variable-number tandem repeats (MIRU-VNTR) and IS900 restriction fragment length polymorphism (RFLP). Combined MIRU-VNTR and SSR typing followed by secondary IS900 RFLP typing is an improved approach to high-resolution genotyping of this pathogen.

摘要

短序列重复（SSR）测序应用于127株鸟分枝杆菌副结核亚种分离株，这些分离株通过分枝杆菌散布重复单元可变数目串联重复序列（MIRU-VNTR）和IS900限制性片段长度多态性（RFLP）进行分型。联合MIRU-VNTR和SSR分型，随后进行二次IS900 RFLP分型，是对该病原体进行高分辨率基因分型的一种改进方法。