Efstratiadis G, Konstantinou D, Chytas I, Vergoulas G
Nephrology Department, Aristotle University of Thessaloniki Hippokratio Hospital, Thessaloniki.
Hippokratia. 2008 Jan;12(1):11-6.
The interaction between chronic heart failure, chronic kidney insufficiency and anemia, form a vicious cycle, termed as the cardio-renal anemia syndrome. The interaction between these three conditions causes deterioration of the cardiac and renal function and increases anemia. Each of the three can cause or be caused by the others.We herein analyze and speculate the mechanisms involved in the pathophysiology of this new syndrome highlighting the main points of interest that seem to expand upon more than one specialty. The cardio-renal anemia syndrome is emerging in the area of clinical investigation with progressively elevated significance. Additionaly we report the data related to anemia treatment as part of therapeutic perspective concerning the management of patients manifesting the profile of this syndrome.
慢性心力衰竭、慢性肾功能不全和贫血之间的相互作用形成了一个恶性循环,称为心肾贫血综合征。这三种情况之间的相互作用会导致心脏和肾脏功能恶化,并加重贫血。三者中的每一种都可能导致其他两者,也可能由其他两者引起。我们在此分析并推测这一新综合征病理生理学中涉及的机制,突出那些似乎跨越不止一个专业领域的主要关注点。心肾贫血综合征正在临床研究领域中逐渐显现,其重要性日益增加。此外,我们报告与贫血治疗相关的数据,作为关于该综合征患者管理的治疗观点的一部分。