Suppr超能文献

[泪阜肿瘤的临床特征与组织病理学]

[Clinical aspects and histopathology of caruncular tumors].

作者信息

Hirsch C, Holz F G, Tetz M, Völcker H E

机构信息

Universitäts-Augenklinik Heidelberg.

出版信息

Klin Monbl Augenheilkd. 1997 Mar;210(3):153-7. doi: 10.1055/s-2008-1035035.

Abstract

BACKGROUND

Histologically the lacrimal caruncle represents a transition zone between the conjunctiva and the skin containing cutaneous, conjunctival and lacrimal elements. This accounts for a variety of histopathological changes.

METHODS

We conducted a retrospective study on the histopathological findings of 65 caruncular lesions which were referred for excisional biopsy between 1974 and 1995 to the Department of Ophthalmology at the University of Heidelberg. The age of the patients ranged from 10-87 years (mean 42 +/- 18.2).

RESULTS

Histopathologic diagnoses included 29 (45%) nevi, 15 (23%) papillomas, 7 (11%) chronic inflammatory lesions and 4 (6%) epidermoid cysts. In addition, 4 (6%) semimalignant and malignant tumours were found including one basalioma, one squamous cell carcinoma and two Kaposi-sarcomas. Among the remaining 8% a dermoid cyst, an accessory lacrimal gland with a retention cyst, an epithelial implantation cyst, a teleangiectatic granuloma and an oncocytoma were diagnosed.

CONCLUSION

These findings suggest that malignant caruncular lesions are rare, however excisional biopsy appears prudent in order to establish the histological diagnosis.

摘要

背景

组织学上,泪阜代表结膜与皮肤之间的过渡区域,包含皮肤、结膜和泪腺成分。这导致了多种组织病理学变化。

方法

我们对1974年至1995年间转诊至海德堡大学眼科进行切除活检的65例泪阜病变的组织病理学结果进行了回顾性研究。患者年龄在10至87岁之间(平均42±18.2岁)。

结果

组织病理学诊断包括29例(45%)痣、15例(23%)乳头状瘤、7例(11%)慢性炎症性病变和4例(6%)表皮样囊肿。此外,发现4例(6%)半恶性和恶性肿瘤,包括1例基底细胞瘤、1例鳞状细胞癌和2例卡波西肉瘤。在其余8%的病例中,诊断出皮样囊肿、伴有潴留囊肿的副泪腺、上皮植入性囊肿、毛细血管扩张性肉芽肿和嗜酸性细胞瘤。

结论

这些发现表明,泪阜恶性病变罕见,但为了确立组织学诊断,切除活检似乎是谨慎的做法。

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验