Viardot-Helmer A, Ott H, Sauer I, Merk H F
Hautklinik, Universitätsklinikum der RWTH Aachen, Pauwelsstrasse 30, 52074 Aachen, Deutschland.
Hautarzt. 2008 Nov;59(11):883-4. doi: 10.1007/s00105-008-1653-5.
During chemoembolization with gemcitabine, mitomycin and cisplatin of a cholangiocellular carcinoma and after receiving iodide contrast media, a 49-year-old patient developed a grade III anaphylactic reaction. We were asked to verify an adverse reaction to contrast media. Using the basophil activation test, we demonstrated a hypersensitivity reaction to cisplatin with distinct induction of CD63-expression on basophilic granulocytes.
在对一名胆管细胞癌患者进行吉西他滨、丝裂霉素和顺铂化疗栓塞期间,以及在接受碘造影剂后,一名49岁患者发生了III级过敏反应。我们被要求核实对造影剂的不良反应。通过嗜碱性粒细胞活化试验,我们证实了对顺铂的超敏反应,嗜碱性粒细胞上明显诱导了CD63表达。