Wang Shwu-Meei, Hsu Chyong-Hsin, Chang Jui-Hsing
Department of Pediatrics, Mackay Memorial Hospital, Taipei, Taiwan.
Pediatr Neonatol. 2008 Jun;49(3):94-6. doi: 10.1016/S1875-9572(08)60020-0.
Congenital candidiasis presents with a variety of clinical features. We report two neonates with congenital candidiasis characterized by diffuse erythematous papules associated with pneumonia and respiratory distress. Candida pseudohyphae were identifiable in skin scrapings. Systemic cultures were negative, but urine and sputum cultures grew Candida albicans. After prompt systemic antifungal therapy, the infants were discharged from hospital with no overt complications. This report highlights the presence of characteristic skin lesions associated with candidal infection, occurring within 24 hours of birth. This is an important observation which could help in the early diagnosis of congenital candidal infection.
先天性念珠菌病有多种临床特征。我们报告了两名患有先天性念珠菌病的新生儿，其特征为弥漫性红斑丘疹，并伴有肺炎和呼吸窘迫。在皮肤刮屑中可识别出念珠菌假菌丝。全身培养为阴性，但尿液和痰液培养培养出白色念珠菌。经过及时的全身抗真菌治疗，婴儿出院时无明显并发症。本报告强调了出生后24小时内出现的与念珠菌感染相关的特征性皮肤病变。这是一项重要的观察结果，有助于先天性念珠菌感染的早期诊断。
