Department of Anatomy, Department of Public Health and Management, Carol Davila University of Medicine and Pharmacy, Bucharest, Romania; Department of Obstetrics and Gynecology, University Emergency Hospital, Bucharest, Romania;
Rom J Morphol Embryol. 2020 Jul-Sep;61(3):673-680. doi: 10.47162/RJME.61.3.05.
Systemic candidiasis is a frequent complication in neonatal units, but congenital systemic candidiasis is an unusual diagnosis, observed in both full-term and preterm infants, with less than 50 cases reported to date. Congenital candidiasis presents with a wide spectrum of symptoms, ranging from diffuse skin eruptions to severe systemic disease, resulting in fetal demise or early neonatal death. Although management guidelines have been published almost two decades ago, due to the rarity of this type of infection, conclusive recommendations are difficult to establish, since they are based on anecdotal experience. In this paper, we present a comprehensive meta-analysis of the current scientific knowledge regarding congenital candidiasis, which spans 54 years and includes a total of 44 cases.
系统性念珠菌病是新生儿病房的常见并发症，但先天性系统性念珠菌病是一种不常见的诊断，在足月和早产儿中均有观察到，迄今为止报告的病例少于 50 例。先天性念珠菌病的表现症状范围广泛，从弥漫性皮疹到严重的全身性疾病，导致胎儿死亡或新生儿早期死亡。尽管管理指南在近二十年前就已发布，但由于这种类型的感染较为罕见，因此难以确定明确的建议，因为这些建议是基于传闻经验。在本文中，我们对当前关于先天性念珠菌病的科学知识进行了全面的荟萃分析，该分析跨越 54 年，共包括 44 例病例。
