Glaser J B, Schachter J, Benes S, Cummings M, Frances C A, McCormack W M
Department of Medicine, State University of New York (SUNY) Health Science Center, Brooklyn 11203.
J Infect Dis. 1991 Oct;164(4):726-30. doi: 10.1093/infdis/164.4.726.
Seventy-six postpubertal women were referred from a municipal hospital emergency room within 60 h of sexual assault for evaluation. Of the 76 victims, 20 (26%) had active Chlamydia trachomatis infection detected by culture (11 subjects), a fourfold serologic titer rise (6), or both (3). The risk of acquiring C. trachomatis infection after sexual assault was 3%-16%. Pelvic inflammatory disease was detected in 8 (11%) of the 76 victims. Bacterial vaginosis was diagnosed in 38 women (50%), at least 8 of whom appeared to have been infected during the assault. Trichomoniasis was found in 17 victims (22%), at least 5 of whom may have acquired the infection at the time of the assault. In view of the high rates of these infections and the poor compliance with follow-up (76% [58/76] kept their appointments), all postpubertal victims of sexual assault should be offered treatment with ceftriaxone, 250 mg intramuscularly, followed by 100 mg of oral doxycycline and 500 mg of oral metronidazole twice daily for 7 days.
76名青春期后女性在遭受性侵犯后60小时内被从一家市级医院急诊室转来接受评估。在这76名受害者中，20名（26%）通过培养（11名受试者）、血清学滴度升高四倍（6名）或两者兼而有之（3名）检测出沙眼衣原体活动性感染。性侵犯后感染沙眼衣原体的风险为3% - 16%。76名受害者中有8名（11%）被检测出患有盆腔炎。38名女性（50%）被诊断为细菌性阴道病，其中至少8名似乎在性侵犯期间被感染。17名受害者（22%）被发现患有滴虫病，其中至少5名可能在性侵犯时感染。鉴于这些感染的高发生率以及随访依从性差（76% [58/76]遵守预约），所有青春期后性侵犯受害者都应接受头孢曲松治疗，250毫克肌肉注射，随后口服100毫克强力霉素和500毫克甲硝唑，每日两次，共7天。
