Rosenbloom S Trent, Brown Steven H, Froehling David, Bauer Brent A, Wahner-Roedler Dietlind L, Gregg William M, Elkin Peter L
Department of Biomedical Informatics, Vanderbilt University, Nashville-TN, USA.
J Am Med Inform Assoc. 2009 Jan-Feb;16(1):81-8. doi: 10.1197/jamia.M2694. Epub 2008 Oct 24.
Interface terminologies are designed to support interactions between humans and structured medical information. In particular, many interface terminologies have been developed for structured computer based documentation systems. Experts and policy-makers have recommended that interface terminologies be mapped to reference terminologies. The goal of the current study was to evaluate how well the reference terminology SNOMED CT could map to and represent two interface terminologies, MEDCIN and the Categorical Health Information Structured Lexicon (CHISL).
Automated mappings between SNOMED CT and 500 terms from each of the two interface terminologies were evaluated by human reviewers, who also searched SNOMED CT to identify better mappings when this was judged to be necessary. Reviewers judged whether they believed the interface terms to be clinically appropriate, whether the terms were covered by SNOMED CT concepts and whether the terms' implied semantic structure could be represented by SNOMED CT.
Outcomes included concept coverage by SNOMED CT for study terms and their implied semantics. Agreement statistics and compositionality measures were calculated.
The SNOMED CT terminology contained concepts to represent 92.4% of MEDCIN and 95.9% of CHISL terms. Semantic structures implied by study terms were less well covered, with some complex compositional expressions requiring semantics not present in SNOMED CT. Among sampled terms, those from MEDCIN were more complex than those from CHISL, containing an average 3.8 versus 1.8 atomic concepts respectively, p<0.001.
Our findings support using SNOMED CT to provide standardized representations of information created using these two terminologies, but suggest that enriching SNOMED CT semantics would improve representation of the external terms.
接口术语旨在支持人类与结构化医学信息之间的交互。特别是,已经为基于计算机的结构化文档系统开发了许多接口术语。专家和政策制定者建议将接口术语映射到参考术语。本研究的目的是评估参考术语SNOMED CT能够多好地映射到并表示两种接口术语MEDCIN和分类健康信息结构化词典(CHISL)。
由人工评审员评估SNOMED CT与这两种接口术语中各500个术语之间的自动映射,在认为必要时,评审员还会在SNOMED CT中进行搜索以确定更好的映射。评审员判断他们是否认为接口术语在临床上是合适的,这些术语是否被SNOMED CT概念所涵盖,以及这些术语的隐含语义结构是否可以由SNOMED CT表示。
结果包括SNOMED CT对研究术语及其隐含语义的概念覆盖。计算了一致性统计和组合性度量。
SNOMED CT术语包含能够表示92.4%的MEDCIN术语和95.9%的CHISL术语的概念。研究术语所隐含的语义结构覆盖得较差,一些复杂的组合表达式需要SNOMED CT中不存在的语义。在抽样术语中,来自MEDCIN的术语比来自CHISL的术语更复杂,分别平均包含3.8个和1.8个原子概念,p<0.001。
我们的研究结果支持使用SNOMED CT来提供使用这两种术语创建的信息的标准化表示,但表明丰富SNOMED CT语义将改善外部术语的表示。