Kubler-Kielb Joanna, Schneerson Rachel, Mocca Chris, Vinogradov Evgeny
National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD 20892, USA.
Carbohydr Res. 2008 Dec 8;343(18):3123-7. doi: 10.1016/j.carres.2008.09.017. Epub 2008 Sep 24.
Plesiomonas shigelloides O17 LPS contains the same O-antigenic polysaccharide chain as a causative agent of dysentery, Shigella sonnei. This polysaccharide can be used as a component of a vaccine against dysentery. Core part of the P. shigelloides O17 LPS was studied using NMR and mass spectrometry and the following structure was proposed: [structure : see text]. Significant similarity of the P. shigelloides O17 LPS core with the structure of the P. shigelloides O54 core was observed.
类志贺邻单胞菌O17脂多糖含有与痢疾致病菌宋内志贺菌相同的O抗原多糖链。这种多糖可作为抗痢疾疫苗的一种成分。利用核磁共振和质谱对类志贺邻单胞菌O17脂多糖的核心部分进行了研究,并提出了以下结构:[结构:见原文]。观察到类志贺邻单胞菌O17脂多糖核心与类志贺邻单胞菌O54核心结构有显著相似性。