Banerjee Anindya, Kumar Suresh, Kulhara Parmanand, Gupta Amod
Department of Psychiatry, Post Graduate Institute of Medical Education and Research (PGIMER), Chandigarh, India.
Indian J Ophthalmol. 2008 Nov-Dec;56(6):469-74. doi: 10.4103/0301-4738.42643.
To estimate depression in patients with age-related macular degeneration (AMD) and study the relationships among depression, visual acuity, and disability.
It was a cross-sectional study with consecutive sampling (n = 53) of patients with AMD aged 50 years and above attending the retina clinic of a tertiary care hospital in North India. Depression, general disability and vision-specific disability were assessed in subjects meeting selection criteria. Assessments were done using the fourth edition of Diagnostic and Statistical Manual of mental disorders (DSM- IV) Geriatric Depression Scale (GDS), Structured Clinical Interview for DSM-IV Axis -I Disorders, Clinical Version (SCID-CV), World Health Organization Disability Assessment Schedule-II (WHODAS-II) and Daily Living Tasks dependent on Vision scale (DLTV). Non-parametric correlation analyses and regression analyses were performed.
Out of 53 participants, 26.4% (n = 14) met DSM-IV criteria for the diagnosis of depressive disorder. Depressed patients had significantly greater levels of general and vision-specific disability than non-depressed patients. General disability was predicted better by depression and vision-specific disability than by visual acuity.
Depression is a major concern in patients with AMD and contributes more to disability than visual impairment.
评估年龄相关性黄斑变性（AMD）患者的抑郁状况，并研究抑郁、视力和残疾之间的关系。
这是一项横断面研究，对印度北部一家三级护理医院视网膜诊所中50岁及以上的AMD患者进行连续抽样（n = 53）。对符合入选标准的受试者进行抑郁、一般残疾和视力特异性残疾评估。评估采用《精神疾病诊断与统计手册》第四版（DSM-IV）老年抑郁量表（GDS）、DSM-IV轴I障碍临床定式访谈临床版（SCID-CV）、世界卫生组织残疾评估量表第二版（WHODAS-II）和视力依赖日常生活任务量表（DLTV）进行。进行了非参数相关分析和回归分析。
53名参与者中，26.4%（n = 14）符合DSM-IV抑郁障碍诊断标准。抑郁患者的一般残疾和视力特异性残疾水平明显高于非抑郁患者。与视力相比，抑郁和视力特异性残疾对一般残疾的预测效果更好。
抑郁是AMD患者的一个主要问题，对残疾的影响比视力损害更大。
