Liu Shu-Li, Li Long, Cheng Wei, Hou Wen-Ying, Huang Liu-Ming, Wang Wen-Ya, Zhang Jun
Department of Pediatric Surgery, Peking University First Hospital, Beijing, China.
J Laparoendosc Adv Surg Tech A. 2009 Apr;19 Suppl 1:S31-5. doi: 10.1089/lap.2008.0119.supp.
The aim of this study was to evaluate the feasibility of laparoscopic hepatojejunostomy for types I and II biliary atresia (BA).
Between April 2003 and July 2007, 10 children with "correctable" types I and II BA were enrolled for the study. They presented with progressive jaundice, pale stools, and elevated aspartate transferase and alanine transferase levels. There were 6 girls and 4 boys, with ages ranging from 23 to 160 days (median,53). All BA had cysts of extrahaptic bile ducts. There were 6 type I and 4 were type II BA. The median diameter of the cysts was 1.5 cm (range, 1.0-1.8). All 10 children underwent laparoscopic cyst excision with Roux-en-Y hepatojejunostomy. Four trocars were inserted. The distal end of the cyst was resected.and a Rouxen-Y hepatojejunostomy was fashioned. The patients were followed up on median for 26 months (range, 4-51).
The median duration of the operation was 3.0 hours (range, 2.4 - 3.2). There were no intraoperative complications. The blood loss was between 5 to 10 mL. Postoperatively, patients passed flatus after 18 hours(range, 16-28), and resumed oral intake in 20 hours (range, 16-30). Normal colored stools were passed after 3 days (range, 2-4). Jaundice started to disappear on postoperative day 10 (range, 7-16). In 6 cases, the total and the direct bilirubin were normalized on postoperative day 14-3 in 3 weeks. One patient had a persistent elevation of bilirubin. The postoperative course was uneventful in all patients. The median postoperable hospital stay was 7 days (range, 5-9). No postoperative complication was found at the follow-up visits.
The laparoscopic Kasai' operation for children with type I or II biliary atresia is feasible, safe, and effective.
本研究旨在评估腹腔镜肝空肠吻合术治疗I型和II型胆道闭锁(BA)的可行性。
2003年4月至2007年7月,10例“可矫正”的I型和II型BA患儿纳入本研究。他们表现为进行性黄疸、陶土样大便以及天冬氨酸转氨酶和丙氨酸转氨酶水平升高。其中有6名女孩和4名男孩,年龄在23至160天之间(中位数为53天)。所有BA患儿均有肝外胆管囊肿。I型BA有6例,II型BA有4例。囊肿的中位直径为1.5厘米(范围为1.0 - 1.8厘米)。所有10例患儿均接受了腹腔镜囊肿切除及Roux-en-Y肝空肠吻合术。插入4个套管针。切除囊肿远端,并构建Roux-en-Y肝空肠吻合术。对患者进行了中位时间为26个月(范围为4 - 51个月)的随访。
手术中位时长为3.0小时(范围为2.4 - 3.2小时)。术中无并发症。出血量在5至10毫升之间。术后,患者在18小时后(范围为16 - 28小时)排气,并在20小时后(范围为16 - 30小时)恢复经口进食。术后3天(范围为2 - 4天)排出正常颜色的大便。黄疸在术后第10天(范围为7 - 16天)开始消退。6例患儿的总胆红素和直接胆红素在术后第14天恢复正常,3周内有3例恢复正常。1例患儿胆红素持续升高。所有患者术后病程平稳。术后住院中位天数为7天(范围为5 - 9天)。随访时未发现术后并发症。
I型或II型胆道闭锁患儿的腹腔镜Kasai手术可行、安全且有效。