Airoldi James, Pereira Leonardo, Cotter Amanda, Gomez Ricardo, Berghella Vincenzo, Prasertcharoensuk Witoon, Rasanen Juha, Chaithongwongwatthana Surasith, Mittal Suneeta, Kearney Etaion, Tolosa Jorge E
Thomas Jefferson University, Philadelphia, Pennsylvania, USA.
Am J Perinatol. 2009 Jan;26(1):63-8. doi: 10.1055/s-0028-1095182. Epub 2008 Oct 31.
We evaluated whether the performance of an amniocentesis in women with a dilated cervix presenting at less than 26 weeks and subsequently managed by a physical exam-indicated cerclage increases the risk of spontaneous preterm birth (PTB) less than 28 weeks. Women between 15 (0)/ (7) to 25 (6)/ (7) weeks' gestation with a dilated cervix (1 to 4 cm) were identified. Multiple exclusion criteria were designated. The primary outcome was PTB less than 28 weeks. One hundred twenty-two women with a dilated cervix between 15 and 25 (6)/ (7) weeks gestational age were identified. Twenty-four (20%) of these had an amniocentesis performed. The unadjusted rate of PTB < 28 weeks differed between women who underwent amniocentesis compared with those who did not (58% versus 34%, respectively, P = 0.02), but after multivariate regression analysis, the performance of an amniocentesis was not an independent contributor to PTB < 28 weeks ( P = 0.90). The performance of an amniocentesis prior to cerclage did not independently contribute to PTB less than 28 weeks.
我们评估了对于孕26周前宫颈扩张且随后接受体格检查指征性宫颈环扎术的女性，进行羊膜腔穿刺术是否会使孕28周前自发早产（PTB）的风险增加。确定了妊娠15（0）/（7）至25（6）/（7）周且宫颈扩张（1至4厘米）的女性。指定了多项排除标准。主要结局是孕28周前的PTB。确定了122名妊娠15至25（6）/（7）周宫颈扩张的女性。其中24名（20%）进行了羊膜腔穿刺术。与未进行羊膜腔穿刺术的女性相比，进行羊膜腔穿刺术的女性孕28周前PTB的未调整发生率有所不同（分别为58%和34%，P = 0.02），但经过多因素回归分析后，羊膜腔穿刺术并非孕28周前PTB的独立影响因素（P = 0.90）。在宫颈环扎术前进行羊膜腔穿刺术并非孕28周前PTB的独立影响因素。
