Lem Kristina Y, Fosgate Geoffrey T, Norby Bo, Steiner Jörg M
Department of Veterinary Integrative Biosciences, College of Veterinary Medicine and Biomedical Sciences, Texas A&M University, College Station, TX 77843, USA.
J Am Vet Med Assoc. 2008 Nov 1;233(9):1425-31. doi: 10.2460/javma.233.9.1425.
To estimate associations between dietary factors and pancreatitis in dogs. Design-Retrospective case-control study.
198 dogs with a clinical diagnosis of pancreatitis and 187 control dogs with a diagnosis of renal failure without clinical evidence of pancreatitis.
Information on signalment, weight, body condition, dietary intake, medical history, diagnostic tests performed, concurrent diseases, treatments, duration of hospitalization, and discharge status was extracted from medical records. Information on dietary intake, signalment, weight, and medical, surgical, and environmental history was collected through a telephone questionnaire. Logistic regression was used to estimate odds ratios (OR) and 95% confidence intervals.
On the basis of information extracted from the medical record, ingesting unusual food items (OR, 4.3) increased the odds of pancreatitis. On the basis of information gathered through the telephone questionnaire, ingesting unusual food items (OR, 6.1), ingesting table scraps the week before diagnosis (OR, 2.2) or throughout life (OR, 2.2), and getting into the trash (OR, 13.2) increased the odds of pancreatitis. Multivariable modeling indicated that reporting exposure to > or = 1 dietary factor during the telephone questionnaire (OR, 2.6), being overweight (OR, 1.3) or neutered (OR, 3.6), previous surgery other than neutering (OR, 21.1), and the interaction between neuter status and previous surgery other than neutering (OR, 0.1) were associated with the odds of pancreatitis.
Results suggested that dietary factors, being neutered, and previous surgery other than neutering increased the odds of pancreatitis in dogs.
评估犬类饮食因素与胰腺炎之间的关联。设计——回顾性病例对照研究。
198只临床诊断为胰腺炎的犬以及187只诊断为肾衰竭且无胰腺炎临床证据的对照犬。
从病历中提取有关动物特征、体重、身体状况、饮食摄入、病史、进行的诊断测试、并发疾病、治疗、住院时间和出院状态的信息。通过电话问卷收集饮食摄入、动物特征、体重以及医疗、手术和环境史的信息。采用逻辑回归来估计比值比（OR）和95%置信区间。
根据从病历中提取的信息，摄入不寻常食物（OR，4.3）会增加患胰腺炎的几率。根据通过电话问卷收集的信息，摄入不寻常食物（OR，6.1）、在诊断前一周（OR，2.2）或一生中（OR，2.2）摄入残羹剩饭以及翻找垃圾（OR，13.2）会增加患胰腺炎的几率。多变量模型表明，在电话问卷中报告暴露于≥1种饮食因素（OR，2.6）、超重（OR，1.3）或已绝育（OR，3.6）、除绝育外的既往手术（OR，21.1）以及绝育状态与除绝育外的既往手术之间的相互作用（OR，0.1）与患胰腺炎的几率相关。
结果表明，饮食因素、绝育状态以及除绝育外的既往手术会增加犬患胰腺炎的几率。
