Foulks Gary N
Department of Ophthalmology and Visual Sciences, University of Louisville School of Medicine, 301 East Muhammad Ali Boulevard, Louisville, KY 40202, USA.
Rheum Dis Clin North Am. 2008 Nov;34(4):987-1000, x. doi: 10.1016/j.rdc.2008.08.008.
Physicians caring for patients who have Sjögren's syndrome often face a particularly difficult task in managing the dry eye that occurs with this disease. The discomfort produced by the condition and the fluctuation of vision attendant to tear film instability are often the most annoying of the clinical symptoms. The understanding of dry eye disease in both its clinical expression and underlying etiopathology has expanded over the past 10 years with implications for management and therapy. The array of potential treatments both topical and systemic has evolved to provide a much more targeted and effective arsenal from which the clinician may choose.
照顾干燥综合征患者的医生在处理该疾病伴发的干眼症时,常常面临一项特别艰巨的任务。这种病症所产生的不适以及泪膜不稳定导致的视力波动,往往是最令人烦恼的临床症状。在过去十年中,人们对干眼症的临床表现和潜在病因病理的认识有所扩展,这对其管理和治疗具有重要意义。局部和全身应用的一系列潜在治疗方法不断发展,为临床医生提供了更多针对性更强且更有效的选择。