Theoretical Neuroscience Group, UMR6152 Institut de Science du Mouvement CNRS, 163 Avenue de Luminy, CP 910, 13288, Marseille Cedex 9, France,
Cogn Neurodyn. 2008 Jun;2(2):115-20. doi: 10.1007/s11571-008-9044-2. Epub 2008 Apr 23.
In absence of all goal-directed behavior, a characteristic network of cortical regions involving prefrontal and cingulate cortices consistently shows temporally coherent fluctuations. The origin of these fluctuations is unknown, but has been hypothesized to be of stochastic nature. In the present paper we test the hypothesis that time delays in the network dynamics play a crucial role in the generation of these fluctuations. By tuning the propagation velocity in a network based on primate connectivity, we scale the time delays and demonstrate the emergence of the resting state networks for biophysically realistic parameters.
在缺乏所有有目标导向行为的情况下，一个包含前额叶和扣带皮层的皮质区域的特征网络始终显示出时间上连贯的波动。这些波动的起源尚不清楚，但有人假设它们具有随机性质。在本文中，我们检验了这样一个假设，即网络动力学中的时滞在这些波动的产生中起着至关重要的作用。通过调整基于灵长类动物连通性的网络传播速度，我们对时滞进行了缩放，并为生物物理上合理的参数展示了静息状态网络的出现。
