Kauer F, Simon J C, Sticherling M
Department of Dermatology and Venerology, Vivantes Klinikum Neukölln, Berlin, Germany.
Dermatology. 2009;218(1):63-6. doi: 10.1159/000173976. Epub 2008 Nov 13.
Scleroderma may present as being strictly limited to the skin, as in morphea, or within a multiorgan disease, as in systemic sclerosis. Accordingly, cutaneous manifestations vary clinically. In nodular or keloidal scleroderma, patients develop lesions that are clinically indistinguishable from a keloid; however, the histopathological findings are more variable. We describe a 16-year-old girl with morpheic lesions for 3-4 years and additional development of keloidal nodules within these lesions. The histological examination revealed a hypertrophic scar besides morphea.
硬皮病可能仅局限于皮肤，如硬斑病，也可能是多器官疾病，如系统性硬化症。因此，皮肤表现临床上各不相同。在结节性或瘢痕疙瘩样硬皮病中，患者出现的皮损在临床上与瘢痕疙瘩难以区分；然而，组织病理学表现则更具多样性。我们描述了一名16岁女孩，有3 - 4年的硬斑病样皮损，且在这些皮损内又出现了瘢痕疙瘩样结节。组织学检查显示除硬斑病外还有肥厚性瘢痕。
