Stewart Scott H, Connors Gerard J
Department of Medicine, School of Medicine and Biomedical Sciences, State University of New York, Buffalo, New York, USA.
Alcohol Res Health. 2004;28(1):5-16.
Screening tests are useful in a variety of settings and contexts, but not all disorders are amenable to screening. Alcohol use disorders (AUDs) and other drinking problems are a major cause of morbidity and mortality and are prevalent in the population; effective treatments are available, and patient outcome can be improved by early detection and intervention. Therefore, the use of screening tests to identify people with or at risk for AUDs can be beneficial. The characteristics of screening tests that influence their usefulness in clinical settings include their validity, sensitivity, and specificity. Appropriately conducted screening tests can help clinicians better predict the probability that individual patients do or do not have a given disorder. This is accomplished by qualitatively or quantitatively estimating variables such as positive and negative predictive values of screening in a population, and by determining the probability that a given person has a certain disorder based on his or her screening results.
筛查测试在各种环境和背景下都很有用,但并非所有疾病都适合进行筛查。酒精使用障碍(AUDs)和其他饮酒问题是发病和死亡的主要原因,且在人群中普遍存在;有效的治疗方法是可用的,早期发现和干预可以改善患者的预后。因此,使用筛查测试来识别患有AUDs或有患AUDs风险的人可能是有益的。影响其在临床环境中有用性的筛查测试特征包括其有效性、敏感性和特异性。适当进行的筛查测试可以帮助临床医生更好地预测个体患者患有或未患有特定疾病的概率。这是通过定性或定量估计诸如人群中筛查的阳性和阴性预测值等变量,并根据某人的筛查结果确定其患有某种疾病的概率来实现的。