手部湿疹分类：一项关于手部湿疹病因及形态学的横断面多中心研究。
Hand eczema classification: a cross-sectional, multicentre study of the aetiology and morphology of hand eczema.
作者信息
Diepgen T L, Andersen K E, Brandao F M, Bruze M, Bruynzeel D P, Frosch P, Gonçalo M, Goossens A, Le Coz C J, Rustemeyer T, White I R, Agner T
机构信息
Department of Social Medicine, Occupational and Environmental Dermatology, University Hospital Heidelberg, Thibautstr. 3, 69115 Heidelberg, Germany.
出版信息
Br J Dermatol. 2009 Feb;160(2):353-8. doi: 10.1111/j.1365-2133.2008.08907.x. Epub 2008 Oct 23.
BACKGROUND
Hand eczema is a long-lasting disease with a high prevalence in the background population. The disease has severe, negative effects on quality of life and sometimes on social status. Epidemiological studies have identified risk factors for onset and prognosis, but treatment of the disease is rarely evidence based, and a classification system for different subdiagnoses of hand eczema is not agreed upon. Randomized controlled trials investigating the treatment of hand eczema are called for. For this, as well as for clinical purposes, a generally accepted classification system for hand eczema is needed.
OBJECTIVES
The present study attempts to characterize subdiagnoses of hand eczema with respect to basic demographics, medical history and morphology.
METHODS
Clinical data from 416 patients with hand eczema from 10 European patch test clinics were assessed.
RESULTS
A classification system for hand eczema is proposed.
CONCLUSIONS
It is suggested that this classification be used in clinical work and in clinical trials.
背景
手部湿疹是一种在普通人群中患病率较高的慢性疾病。该疾病对生活质量有时还对社会地位有严重的负面影响。流行病学研究已经确定了发病和预后的风险因素，但该疾病的治疗很少基于证据，并且手部湿疹不同亚诊断的分类系统尚未达成共识。需要开展调查手部湿疹治疗的随机对照试验。为此，以及出于临床目的，需要一个普遍接受的手部湿疹分类系统。
目的
本研究试图根据基本人口统计学、病史和形态学对手部湿疹的亚诊断进行特征描述。
方法
评估了来自10家欧洲斑贴试验诊所的416例手部湿疹患者的临床数据。
结果
提出了一种手部湿疹分类系统。
结论
建议在临床工作和临床试验中使用该分类。
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