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头孢克肟与其他口服抗生素对含BRO-1和BRO-2的成人卡他莫拉菌（布兰汉菌属）临床分离株及流感嗜血杆菌的活性比较。

Comparison of the activity of cefixime and activities of other oral antibiotics against adult clinical isolates of Moraxella (Branhamella) catarrhalis containing BRO-1 and BRO-2 and Haemophilus influenzae.

作者信息

Nash D R, Flanagan C, Steele L C, Wallace R J

机构信息

Department of Microbiology, University of Texas Health Center, Tyler 75710.

出版信息

Antimicrob Agents Chemother. 1991 Jan;35(1):192-4. doi: 10.1128/AAC.35.1.192.

DOI:10.1128/AAC.35.1.192
PMID:1901696
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC244967/
Abstract

MICs of 10 oral antibiotics were determined for 105 Moraxella catarrhalis and 96 Haemophilus influenzae isolates from adults. A two- to fourfold increase in MICs of oral cephalosporins was seen in the presence of BRO-1 but not with TEM-1 or BRO-2. The MICs of cefixime for 90% of strains of H. influenzae (0.125 microgram/ml) and M. catarrhalis (0.25 microgram/ml) were 8- to 64-fold lower than those of other oral cephalosporins.

摘要

对从成人中分离出的105株卡他莫拉菌和96株流感嗜血杆菌测定了10种口服抗生素的最低抑菌浓度（MIC）。在存在BRO - 1的情况下，口服头孢菌素的MIC出现了2至4倍的增加，但在存在TEM - 1或BRO - 2的情况下则未出现这种情况。90%的流感嗜血杆菌菌株（0.125微克/毫升）和卡他莫拉菌菌株（0.25微克/毫升）对头孢克肟的MIC比其他口服头孢菌素低8至64倍。

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本文引用的文献

1
Comparative in vitro activity and beta-lactamase stability of FR 17027, a new orally active cephalosporin.新型口服活性头孢菌素FR 17027的体外活性及β-内酰胺酶稳定性比较
Antimicrob Agents Chemother. 1984 Aug;26(2):174-80. doi: 10.1128/AAC.26.2.174.
2
Homogeneity of transferable tetracycline-resistance determinants in Haemophilus species.嗜血杆菌属中可转移四环素抗性决定子的同源性
J Infect Dis. 1984 Jun;149(6):1028-9. doi: 10.1093/infdis/149.6.1028.
3
In vitro evaluation of cefixime (FK027, FR17027, CL284635): spectrum against recent clinical isolates, comparative antimicrobial activity, beta-lactamase stability, and preliminary susceptibility testing criteria.头孢克肟（FK027、FR17027、CL284635）的体外评估：对近期临床分离株的抗菌谱、抗菌活性比较、β-内酰胺酶稳定性及初步药敏试验标准
Diagn Microbiol Infect Dis. 1986 Jul;5(2):151-62. doi: 10.1016/0732-8893(86)90117-3.
4
Influence of growth medium and supplement on growth of Haemophilus influenzae and on antibacterial activity of several antibiotics.生长培养基和添加剂对流感嗜血杆菌生长及几种抗生素抗菌活性的影响。
J Clin Microbiol. 1987 Apr;25(4):650-5. doi: 10.1128/jcm.25.4.650-655.1987.
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Isoelectric focusing of beta-lactamases from sputum and middle ear isolates of Branhamella catarrhalis recovered in the United States.对在美国分离出的卡他布兰汉菌痰液和中耳分离株中的β-内酰胺酶进行等电聚焦分析。
Drugs. 1986;31 Suppl 3:48-54. doi: 10.2165/00003495-198600313-00012.
6
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8
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Am Rev Respir Dis. 1988 Mar;137(3):695-9. doi: 10.1164/ajrccm/137.3.695.
9
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Am J Med. 1988 Sep 16;85(3A):6-13. doi: 10.1016/0002-9343(88)90457-3.