头孢克肟与其他口服抗生素对含BRO-1和BRO-2的成人卡他莫拉菌（布兰汉菌属）临床分离株及流感嗜血杆菌的活性比较。
Comparison of the activity of cefixime and activities of other oral antibiotics against adult clinical isolates of Moraxella (Branhamella) catarrhalis containing BRO-1 and BRO-2 and Haemophilus influenzae.
作者信息
Nash D R, Flanagan C, Steele L C, Wallace R J
机构信息
Department of Microbiology, University of Texas Health Center, Tyler 75710.
出版信息
Antimicrob Agents Chemother. 1991 Jan;35(1):192-4. doi: 10.1128/AAC.35.1.192.
Abstract
MICs of 10 oral antibiotics were determined for 105 Moraxella catarrhalis and 96 Haemophilus influenzae isolates from adults. A two- to fourfold increase in MICs of oral cephalosporins was seen in the presence of BRO-1 but not with TEM-1 or BRO-2. The MICs of cefixime for 90% of strains of H. influenzae (0.125 microgram/ml) and M. catarrhalis (0.25 microgram/ml) were 8- to 64-fold lower than those of other oral cephalosporins.
摘要
对从成人中分离出的105株卡他莫拉菌和96株流感嗜血杆菌测定了10种口服抗生素的最低抑菌浓度（MIC）。在存在BRO - 1的情况下，口服头孢菌素的MIC出现了2至4倍的增加，但在存在TEM - 1或BRO - 2的情况下则未出现这种情况。90%的流感嗜血杆菌菌株（0.125微克/毫升）和卡他莫拉菌菌株（0.25微克/毫升）对头孢克肟的MIC比其他口服头孢菌素低8至64倍。
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