Machka K, Balg H, Braveny I
Institute of Medical Microbiology, Technical University of Munich, FRG.
Eur J Clin Microbiol Infect Dis. 1988 Dec;7(6):812-4. doi: 10.1007/BF01975058.
The activity of sulbactam/ampicillin, aztreonam, cefetamet, cefixime, ciprofloxacin, enoxacin, fleroxacin and ofloxacin was determined against 160 Haemophilus influenzae strains using a standardized microdilution method. The strains were categorized into four groups according to beta-lactamase production and their resistance to ampicillin, chloramphenicol, erythromycin, tetracycline and cotrimoxazole. All isolates tested, regardless of their beta-lactamase production or resistance to the above mentioned drugs, were susceptible to the nine antibiotics. The most active antimicrobial agents were aztreonam, cefixime, and the two quinolone derivatives ciprofloxacin and ofloxacin.
采用标准化微量稀释法测定了舒巴坦/氨苄西林、氨曲南、头孢他美、头孢克肟、环丙沙星、依诺沙星、氟罗沙星和氧氟沙星对160株流感嗜血杆菌的活性。根据β-内酰胺酶产生情况以及它们对氨苄西林、氯霉素、红霉素、四环素和复方新诺明的耐药性，将这些菌株分为四组。所有测试的分离株，无论其β-内酰胺酶产生情况或对上述药物的耐药性如何，均对这9种抗生素敏感。活性最强的抗菌药物是氨曲南、头孢克肟以及两种喹诺酮衍生物环丙沙星和氧氟沙星。
