Gupta Shailesh K, Brar Vikram S, Keshavamurthy Ravi, Chalam Kakarla V
University of Florida-College of Medicine, Department of Ophthalmology, Jacksonville, Florida, USA.
Cases J. 2008 Nov 18;1(1):322. doi: 10.1186/1757-1626-1-322.
A case of aplastic anemia diagnosed during pregnancy, which developed bilateral disc edema and acute pre-retinal hemorrhage leading to vision loss.
A 20 year old primagravid female developed acute vision loss in her right eye, during hospitalization for treatment of aplastic anemia diagnosed during her pregnancy. Her best-corrected visual acuity (BCVA) was hand motions and fundus evaluation revealed a large pre-macular hemorrhage in the right eye (OD) and bilateral disc edema. Neuro-imaging studies did not reveal any signs of intracranial mass lesion or edema.
There was resolution of the disc edema with improvement in the pre-macular hemorrhage resulting in 20/50 vision in the right eye, following supportive transfusions. Ophthalmic manifestations developing in a pregnant patient with aplastic anemia can be successfully managed with supportive care including red blood cell and platelet transfusions.
一名妊娠期诊断为再生障碍性贫血的患者，出现双侧视盘水肿和急性视网膜前出血，导致视力丧失。
一名20岁初产妇，在因妊娠期诊断的再生障碍性贫血住院治疗期间，右眼出现急性视力丧失。她的最佳矫正视力（BCVA）为手动，眼底检查显示右眼（OD）有一大片黄斑前出血和双侧视盘水肿。神经影像学检查未发现任何颅内占位性病变或水肿迹象。
在进行支持性输血后，视盘水肿消退，黄斑前出血改善，右眼视力达到20/50。再生障碍性贫血孕妇出现的眼部表现可通过包括红细胞和血小板输血在内的支持性护理成功处理。
