Kharwar Ravindra N, Verma Vijay C, Kumar Anuj, Gond Surendra K, Harper James K, Hess Wilford M, Lobkovosky Emil, Ma Cong, Ren Yuhao, Strobel Gary A
Mycopathology and Microbial Technology Laboratory, Department of Botany, Banaras Hindu University, Varanasi 221005, India.
Curr Microbiol. 2009 Mar;58(3):233-8. doi: 10.1007/s00284-008-9313-7. Epub 2008 Nov 19.
The endophytic fungus Chloridium sp. produces javanicin under liquid and solid media culture conditions. This highly functionalized naphthaquinone exhibits strong antibacterial activity against Pseudomonas spp., representing pathogens to both humans and plants. The compound was crystallized and the structure was elucidated by X-ray crystallography. The X-ray structure confirms the previously elucidated structure of the compound that was done under standard spectroscopic methods. The importance of javanicin in establishing symbiosis between Chloridium sp. and its host plant, Azadirachta indica, is briefly discussed.
内生真菌绿胶杯菌（Chloridium sp.）在液体和固体培养基培养条件下产生爪哇尼辛。这种高度官能化的萘醌对假单胞菌属表现出强烈的抗菌活性，假单胞菌属是对人类和植物均有致病性的病原体。该化合物被结晶，并通过X射线晶体学阐明了其结构。X射线结构证实了之前通过标准光谱方法阐明的该化合物的结构。文中简要讨论了爪哇尼辛在绿胶杯菌与其宿主植物印楝之间建立共生关系中的重要性。
