关于在以色列产KPC-3的肺炎克雷伯菌的一个高流行克隆株的首次报告，该克隆株在基因上与一株在美国引起暴发的菌株相关。
First report on a hyperepidemic clone of KPC-3-producing Klebsiella pneumoniae in Israel genetically related to a strain causing outbreaks in the United States.
作者信息
Navon-Venezia Shiri, Leavitt Azita, Schwaber Mitchell J, Rasheed J Kamile, Srinivasan Arjun, Patel Jean B, Carmeli Yehuda
机构信息
Division of Epidemiology, Tel Aviv Sourasky Medical Center, Israel.
出版信息
Antimicrob Agents Chemother. 2009 Feb;53(2):818-20. doi: 10.1128/AAC.00987-08. Epub 2008 Nov 24.
Abstract
A highly epidemic carbapenem-resistant clone of KPC-3-producing Klebsiella pneumoniae emerged in Israel in 2006, causing a nationwide outbreak. This clone was genetically related to outbreak strains from the United States isolated in 2000 but differed in KPC-carrying plasmids. The threat of the global spread of hyperepidemic, extensively drug-resistant bacterial strains should be recognized and confronted.
摘要
2006年，以色列出现了一种产KPC-3的肺炎克雷伯菌的高流行性耐碳青霉烯克隆株，引发了全国性的疫情爆发。该克隆株在基因上与2000年在美国分离出的疫情菌株有关，但携带KPC的质粒有所不同。应认识到并应对高流行性、广泛耐药细菌菌株全球传播的威胁。
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