Department of Pediatric Dentistry, Faculty of Medical Sciences in Zabrze, Medical University of Silesia, 40-055 Katowice, Poland.
Department of Medical and Molecular Biology, Faculty of Medical Sciences in Zabrze, Medical University of Silesia, 40-055 Katowice, Poland.
Int J Environ Res Public Health. 2022 Jul 17;19(14):8697. doi: 10.3390/ijerph19148697.
(1) Background: This pilot retrospective cohort research study regarded the frequency of the prevalence of molar-incisor hypomineralization (MIH) in a population of Silesian children in Poland. The evaluation of the potential environmental etiological factors was performed and the correlation between the environmental factors and MIH was analyzed. (2) Methods: A total of 613 children were randomly enrolled in the pilot study (9.0 years ± 1.9). A survey was carried out with mothers regarding the potential exposure to environmental etiological factors of MIH in their children. The patients’ clinical assessments were carried out in the dental unit. (3) Results: The frequency of prevalence of MIH in the population of Silesian children was established at the level of 6.2% (p < 0.05). MIH symptoms were significantly associated with otitis in early childhood (OR = 2.50), atopic dermatitis (OR = 5.69), and premature delivery before 38 weeks of pregnancy (OR = 2.88). (4) Conclusions: MIH was observed in 6.2% of the population of Silesian children, and there was a relationship between environmental risk factors such as otitis, atopic dermatitis, premature birth, and MIH expression. Therefore, further research is needed to determine the influence of pre-, peri-, postnatal, and prophylactic factors on the frequency and severity of MIH symptoms in children.
(1) 背景：本研究是一项前瞻性回顾性队列研究，旨在调查波兰西里西亚地区儿童的低龄恒磨牙牙釉质发育不全（MIH）患病率。评估了潜在的环境病因因素，并分析了环境因素与 MIH 之间的相关性。(2) 方法：共纳入 613 名儿童进行了前瞻性研究（9.0 岁±1.9 岁）。对母亲进行了关于儿童 MIH 潜在环境病因暴露的调查。在牙科诊室对患者进行了临床评估。(3) 结果：发现西里西亚儿童的 MIH 患病率为 6.2%（p＜0.05）。MIH 症状与儿童早期的中耳炎（OR=2.50）、特应性皮炎（OR=5.69）和 38 周妊娠前早产（OR=2.88）显著相关。(4) 结论：在西里西亚儿童中，观察到 6.2%的人群存在 MIH，环境危险因素（如中耳炎、特应性皮炎、早产）与 MIH 表达之间存在关系。因此，需要进一步研究来确定产前、围产期和产后以及预防性因素对儿童 MIH 症状的频率和严重程度的影响。
