Grassi Michael A, Mazzulla D Anthony, Knudtson Michael D, Huang Wendy W, Lee Kristine E, Klein Barbara E, Nicolae Dan L, Klein Ronald
Department of Surgery, University of Chicago, Illinois 60637, USA.
Am J Ophthalmol. 2009 Mar;147(3):501-4. doi: 10.1016/j.ajo.2008.09.016. Epub 2008 Dec 3.
To determine whether patient self-report of prior laser treatment can be used as a reliable tool for assessing the presence of severe diabetic retinopathy.
This was a retrospective study on two groups of diabetic subjects.
One hundred patients with diabetes were recruited from the general eye and retina clinics at the University of Chicago Hospitals. The patients were asked, "Have you ever received laser treatment for your diabetic eye disease (DED)?" A chart review was then conducted noting if the patient had received either focal laser treatment for diabetic macular edema or panretinal photocoagulation for proliferative diabetic retinopathy. Data from the Wisconsin Epidemiological Study of Diabetic Retinopathy (WESDR) were also analyzed. Participant responses to the question "Have you had laser photocoagulation treatment for your eyes?" were analyzed with documentation of photocoagulation scars determined by grading seven-standard field color fundus photographs.
In the University of Chicago group, 96 of 100 (96%) of patients were accurate in reporting whether they had received previous laser treatment for DED (sensitivity 95.8%, specificity 96.1%, and positive predictive value 88.5%). In the WESDR analysis, 2,329 of 2,348 (99%) of participants were accurate in reporting whether they had prior laser treatment for DED (sensitivity 96.0%, specificity 99.5%, and positive predictive value 95.6%).
The high sensitivity and specificity of our results validate the use of patient self-report as a useful tool in assessing past laser treatment for severe diabetic retinopathy. Patient self-report may be a useful surrogate to clinical examination or medical record review to determine the presence of severe diabetic retinopathy.
确定患者对既往激光治疗的自我报告是否可作为评估重度糖尿病视网膜病变存在情况的可靠工具。
这是一项针对两组糖尿病患者的回顾性研究。
从芝加哥大学医院的普通眼科和视网膜诊所招募了100名糖尿病患者。询问患者:“您是否曾因糖尿病眼病(DED)接受过激光治疗?”然后进行病历审查,记录患者是否接受过针对糖尿病性黄斑水肿的局部激光治疗或针对增殖性糖尿病视网膜病变的全视网膜光凝治疗。还分析了来自威斯康星糖尿病视网膜病变流行病学研究(WESDR)的数据。通过对七标准视野彩色眼底照片进行分级来确定光凝瘢痕的记录,分析参与者对“您是否接受过眼部激光光凝治疗?”这一问题的回答。
在芝加哥大学组中,100名患者中有96名(96%)准确报告了他们是否曾因DED接受过激光治疗(敏感性95.8%,特异性96.1%,阳性预测值88.5%)。在WESDR分析中,2348名参与者中有2329名(99%)准确报告了他们是否曾因DED接受过激光治疗(敏感性96.0%,特异性99.5%,阳性预测值95.6%)。
我们结果的高敏感性和特异性证实了患者自我报告可作为评估既往重度糖尿病视网膜病变激光治疗的有用工具。患者自我报告可能是临床检查或病历审查的有用替代方法,用于确定重度糖尿病视网膜病变的存在情况。