Carrillo Eugenia, Moreno Javier
Centro de Investigaciones Biológicas, Consejo Superior de Investigaciones Científicas (CSIC), C/Ramiro de Maeztu 9, 28040 Madrid, Spain.
Vet Immunol Immunopathol. 2009 Mar 15;128(1-3):67-70. doi: 10.1016/j.vetimm.2008.10.310. Epub 2008 Oct 17.
Cytokines play a decisive role in the regulation of the immune response directed against Leishmania infantum, determining the prevention or progression of the infection. This review focuses on advances in the canine immune response knowledge over the recent years and examines the principal role of the cytokine pattern elicited after infection with L. infantum.
细胞因子在针对婴儿利什曼原虫的免疫反应调节中起决定性作用,决定感染的预防或进展。本综述着重介绍近年来犬类免疫反应知识的进展,并探讨感染婴儿利什曼原虫后引发的细胞因子模式的主要作用。