Pellegatti Laurent, Zhang Jian, Drahos Bohuslav, Villette Sandrine, Suzenet Franck, Guillaumet Gérald, Petoud Stéphane, Tóth Eva
Centre de Biophysique Moléculaire, CNRS, 45071 Orléans, France.
Chem Commun (Camb). 2008 Dec 28(48):6591-3. doi: 10.1039/b817343e. Epub 2008 Nov 12.
We report two prototype Ln(3+) complexes that address requirements for both MRI and luminescence imaging and we demonstrate that the presence of two H(2)O molecules bound to the Ln(3+), beneficial for MRI applications of the Gd(3+) analogue, is not a major limitation for the development of NIR luminescent agents.
我们报道了两种满足磁共振成像(MRI)和发光成像要求的Ln(3+)配合物原型,并证明与Ln(3+)结合的两个H₂O分子的存在,虽然对Gd(3+)类似物的MRI应用有益,但并非近红外发光剂开发的主要限制因素。