Becerril Angeles Martín, Vázquez Merino Carlos L, Angeles Garay Ulises, Alvarado Moctezuma Luis E, Vilchis Guízar Elena
Servicio de Alergia e Inmunología Clínica, Hospital de Especialidades Centro Médico Nacional La Raza, IMSS.
Rev Alerg Mex. 2008 May-Jun;55(3):85-91.
A population aged 65 and over has been increasing in many countries, including Mexico. Allergic diseases are common in this age group, asthma prevalence has been reported between 2 and 17% in elderly people. There is no data about allergic diseases prevalence in elderly Mexican people.
To know the prevalence of some allergic diseases, allergen sensitization and total IgE serum concentration in a sample of subjects older than 60 years residents in Mexico City.
We included 333 elderly subjects, were included 281 females (84%) and 52 males, with an age-average of 67.2 +/- 5.4, who were attending a social security recreative center. Medical files were made to each one elderly subject, including atopic personal history; skin tests were performed with 10 allergens, histamine and negative controls; and total serum IgE was measured by ELISA. Analysis was made with descriptive statistics, Spearman's coefficient and chi square.
Allergic diseases were present in 10.8% of the subjects, asthma in 3.6%, allergic rhinitis in 3.6%, urticaria in 2.7%, atopic dermatitis in 0.6% and allergic conjunctivitis in 0.3%, 24% had data of adverse drug reactions and 6.9% referred venom insect hypersensitivity. Skin tests results were positive in 84 subjects (25.2%). In the group of 60-69 years it was observed a significant increase in IgE concentration (p < 0.01), we didn't find a significant correlation between IgE levels and both allergic symptoms and skin tests results.
The prevalence of allergic diseases, total IgE levels and allergen sensitization in elderly people were similar to studies in other countries, but with a lower pattern than in younger Mexican population.
包括墨西哥在内的许多国家，65岁及以上的人口一直在增加。过敏性疾病在这个年龄组中很常见，据报道老年人哮喘患病率在2%至17%之间。目前尚无关于墨西哥老年人群过敏性疾病患病率的数据。
了解墨西哥城60岁以上居民样本中某些过敏性疾病的患病率、过敏原致敏情况和总IgE血清浓度。
我们纳入了333名老年受试者，其中281名女性（84%）和52名男性，平均年龄为67.2±5.4岁，他们均来自一个社会保障娱乐中心。为每位老年受试者建立了医疗档案，包括特应性个人病史；用10种过敏原、组胺和阴性对照进行皮肤试验；并用酶联免疫吸附测定法测量总血清IgE。采用描述性统计、Spearman系数和卡方进行分析。
10.8%的受试者患有过敏性疾病，哮喘患病率为3.6%，过敏性鼻炎患病率为3.6%，荨麻疹患病率为2.7%，特应性皮炎患病率为0.6%，过敏性结膜炎患病率为0.3%，24%的受试者有药物不良反应数据，6.9%的受试者有蜂毒昆虫过敏反应。84名受试者（25.2%）的皮肤试验结果呈阳性。在60 - 69岁年龄组中，观察到IgE浓度显著升高（p < 0.01），我们未发现IgE水平与过敏症状及皮肤试验结果之间存在显著相关性。
老年人过敏性疾病的患病率、总IgE水平和过敏原致敏情况与其他国家的研究相似，但低于墨西哥年轻人群的患病率。
