Goralska M, Ferrell J, Harned J, Lall M, Nagar S, Fleisher L N, McGahan M C
Department of Molecular Biomedical Sciences, North Carolina State University, Raleigh, NC 27606, USA.
Exp Eye Res. 2009 Feb;88(2):204-15. doi: 10.1016/j.exer.2008.10.026. Epub 2008 Nov 21.
This review article covers all aspects of iron metabolism, which include studies of iron levels within the eye and the processes used to maintain normal levels of iron in ocular tissues. In addition, the involvement of iron in ocular pathology is explored. In each section there is a short introduction to a specific metabolic process responsible for iron homeostasis, which for the most part has been studied in non-ocular tissues. This is followed by a summary of our current knowledge of the process in ocular tissues.
这篇综述文章涵盖了铁代谢的各个方面,包括对眼内铁水平的研究以及维持眼组织中铁正常水平所采用的过程。此外,还探讨了铁在眼部病理学中的作用。在每个部分,都对负责铁稳态的特定代谢过程进行了简短介绍,其中大部分是在非眼组织中进行研究的。随后是我们目前对眼组织中该过程的认识总结。