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药用植物可能是抗氧化剂的良好来源:喀麦隆的案例研究。

Medicinal plants can be good source of antioxidants: case study in Cameroon.

作者信息

Agbor Gabriel A, Kuate Dieudonne, Oben Julius E

机构信息

Centre of Research on Medicinal Plants and Traditional Medicine, Institute of Medical Research and Medicinal Plants Studies, P.O. Box 6163, Yaoundé, Cameroon.

出版信息

Pak J Biol Sci. 2007 Feb 15;10(4):537-44. doi: 10.3923/pjbs.2007.537.544.

Abstract

Extracts of 42 medicinal plants used for the treatment of anaemia, diabetes, AIDS, malaria and obesity were screened for phytochemical substances and antioxidant potentials. The plant extracts were prepared as hydrolysed (for total antioxidant) and non-hydrolysed (for free antioxidant). Extracts were analysed using three different assay methods for antioxidant analysis: Folin (Folin Ciocalteu reagent), FRAP (Ferric Reducing Antioxidant Power) and DPPH (1,1-diphenyl-2-picrylhydrazyl). The leaves of Alchornea cordifolia showed the highest antioxidant properties as determined by both Folin and FRAP free antioxidant, followed by Dacryodes edulis and Ocimum basilicum in FRAP and by Dacryodes edulis, Harungana madagascariensis for Folin and DPPH method. For total antioxidant activity, Alchornea cordifolia was ranked first followed by Dacryodes edulis, Harungana madagascariensis, Ocimum basilicum for the FRAP method while for the Folin method Harungana madagascariensis occupied the first position followed by Cylicodiscus gabunensis, Ocimum basilicum, Coleus coprosifolius, Alchornea cordifolia, Dacryodes edulis. All the plants show some antioxidant activity irrespective of the method used. The phytochemical studies revealed the presents of important bioactive constituents with antioxidant activity that may have some medicinal properties.

摘要

对用于治疗贫血、糖尿病、艾滋病、疟疾和肥胖症的42种药用植物提取物进行了植物化学物质和抗氧化潜力筛查。植物提取物制备成水解提取物(用于总抗氧化剂)和非水解提取物(用于游离抗氧化剂)。使用三种不同的抗氧化分析测定方法对提取物进行分析:福林法(福林-西奥尔特试剂)、铁还原抗氧化能力法(FRAP)和1,1-二苯基-2-苦基肼法(DPPH)。根据福林法和FRAP游离抗氧化剂测定,心叶山麻杆叶显示出最高的抗氧化性能,其次是在FRAP法中油梨和罗勒,在福林法和DPPH法中油梨、马达加斯加哈伦加那。对于总抗氧化活性,在心叶山麻杆叶在FRAP法中排名第一,其次是油梨、马达加斯加哈伦加那、罗勒;而在福林法中马达加斯加哈伦加那占据首位,其次是加蓬轮叶豆、罗勒、棒叶鞘蕊花、心叶山麻杆叶、油梨。无论使用何种方法,所有植物均显示出一定的抗氧化活性。植物化学研究揭示了具有抗氧化活性的重要生物活性成分的存在,这些成分可能具有一些药用特性。

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