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番泻花的植物化学与抗菌活性初步研究

Preliminary investigation on the phytochemistry and antimicrobial activity of Senna alata L. flower.

作者信息

Idu M, Omonigho S E, Igeleke C L

机构信息

Department of Botany, University of Benin, PMB 1154, Benin City, Nigeria.

出版信息

Pak J Biol Sci. 2007 Mar 1;10(5):806-9. doi: 10.3923/pjbs.2007.806.809.

DOI:10.3923/pjbs.2007.806.809
PMID:19069869
Abstract

Preliminary studies on the phytochemistry and extracts of water, methanol, chloroform and petroleum ether, of Senna alata flowers were examined for antimicrobial properties. Extracts tested at a final concentration of 500 microg mL(-1) produced in vitro antimicrobial activities in assays against clinical isolates of Staphylococus aureus, Candida albicans, Escherichia coli, Proteus vulgaris, Pseudomonans aureginosa and Bacillus subtilis. The zones of inhibitions produced by the extracts in agar diffusion assay against the test micro organisms ranged from 4 to 10 mm while the gentamycin antibiotic control, produced zones that measured 5 mm. Preliminary phytochemical analysis of the plant extracts showed the presence of phenols, tannins, anthraquinoes, saponins, flavonoids.

摘要

对番泻花的植物化学以及水、甲醇、氯仿和石油醚提取物进行了初步研究,检测其抗菌特性。在针对金黄色葡萄球菌、白色念珠菌、大肠杆菌、普通变形杆菌、铜绿假单胞菌和枯草芽孢杆菌临床分离株的试验中,最终浓度为500微克/毫升的提取物产生了体外抗菌活性。提取物在琼脂扩散试验中对测试微生物产生的抑菌圈范围为4至10毫米,而庆大霉素抗生素对照产生的抑菌圈为5毫米。对植物提取物的初步植物化学分析表明存在酚类、单宁、蒽醌、皂苷、黄酮类化合物。

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