植物化学成分和 Peltophorum pterocarpum（DC.）Baker ex Heyne 的花的抗菌功效。

Phytochemical constituents and antibacterial efficacy of the flowers of Peltophorum pterocarpum (DC.) Baker ex Heyne.

机构信息

Centre for Biodiversity and Biotechnology, Department of Botany, N.M. Christian College, Marthandam, Tamilnadu, India.

出版信息

Asian Pac J Trop Med. 2011 Sep;4(9):735-8. doi: 10.1016/S1995-7645(11)60183-1.

DOI:10.1016/S1995-7645(11)60183-1

PMID:21967698

Abstract

OBJECTIVE

To investigate the preliminary phytochemistry and antibacterial activity of the flower extract of Peltophorum pterocarpum .

METHODS

Phytochemical analysis was done by using the standard methods given by Harbone. The methanolic flower extract were tested against Escherichia coli, Klebsiella pneumonia, Pseudomonas aeruginosa, Staphylococcus aureus, Bacillus cereus, Salmonella typhi, Serratia marsecens, Acinetobacter baumannii, Enterobacter sp., Proteus mirabilis, Enterococcus faecalis and Streptococcus pyogenes by the agar disc diffusion method.

RESULTS

Preliminary phytochemical screening of flower extract showed the presence of phenolic compounds, flavonoids, saponins, steroids, tannins, xanthoproteins, carboxylic acids, coumarins and carbohydrates. The flower extract of Peltophorum pterocarpum showed significant activity against four gram positive (Staphylococcus aureus, Bacillus cereus, Enterococcus faecalis and Streptococcus pyogenes) and three gram negative bacteria (Proteus mirabilis, Acinetobacter baumannii and Serratia marsecens), out of 12 pathogenic bacteria studied.

CONCLUSIONS

The findings of the present study confirm the presence of significant antibacterial activity against human pathogens in the flowers of Peltophorum pterocarpum.

摘要

目的

研究紫檀花提取物的初步植物化学和抗菌活性。

方法

采用哈本内标准方法进行植物化学分析。采用琼脂圆盘扩散法检测甲醇提取的紫檀花提取物对大肠埃希菌、肺炎克雷伯菌、铜绿假单胞菌、金黄色葡萄球菌、蜡状芽孢杆菌、伤寒沙门氏菌、粘质沙雷氏菌、鲍曼不动杆菌、肠杆菌属、奇异变形杆菌、粪肠球菌和化脓性链球菌的抗菌活性。

结果

紫檀花提取物的初步植物化学筛选显示存在酚类化合物、类黄酮、皂苷、类固醇、单宁、黄蛋白、羧酸、香豆素和碳水化合物。紫檀花提取物对 12 种致病菌中的 4 种革兰氏阳性菌（金黄色葡萄球菌、蜡状芽孢杆菌、粪肠球菌和化脓性链球菌）和 3 种革兰氏阴性菌（奇异变形杆菌、鲍曼不动杆菌和粘质沙雷氏菌）表现出显著的活性。