• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

The molecular evolution of ZFY-related genes in birds and mammals.

作者信息

Lanfear J, Holland P W

机构信息

Department of Zoology, University of Oxford, UK.

出版信息

J Mol Evol. 1991 Apr;32(4):310-5. doi: 10.1007/BF02102189.

DOI:10.1007/BF02102189
PMID:1907665
Abstract

We report the isolation and nucleotide sequence determination of clones derived from five ZFY-related zinc-finger genes from birds and mammals. These sequences are analyzed with reference to the previously published human genes, ZFX and ZFY, and mouse genes, Zfx, Zfa, Zfy-1, and Zfy-2. The analysis indicates that ZFY-related genes are highly conserved in birds and mammals, and that the rate of nucleotide substitution in the Y-linked genes is not as high as predicted. However, the mouse Zfy-1 and Zfy-2 genes are markedly divergent members of the ZFY gene family; we suggest this relates to X-inactivation of the mouse gene Zfx.

摘要

相似文献

1
The molecular evolution of ZFY-related genes in birds and mammals.
J Mol Evol. 1991 Apr;32(4):310-5. doi: 10.1007/BF02102189.
2
Mouse Zfx protein is similar to Zfy-2: each contains an acidic activating domain and 13 zinc fingers.小鼠Zfx蛋白与Zfy-2相似：二者均含有一个酸性激活结构域和13个锌指结构。
Mol Cell Biol. 1990 Feb;10(2):681-8. doi: 10.1128/mcb.10.2.681-688.1990.
3
Contrasting rates of nucleotide substitution in the X-linked and Y-linked zinc finger genes.X 连锁和 Y 连锁锌指基因中核苷酸替换率的对比
J Mol Evol. 1994 Dec;39(6):569-78. doi: 10.1007/BF00160402.
4
Differential rates of evolution for the ZFY-related zinc finger genes, Zfy, Zfx, and Zfa in the mouse genus Mus.小家鼠属中与ZFY相关的锌指基因Zfy、Zfx和Zfa的不同进化速率。
Mol Biol Evol. 2003 Jun;20(6):999-1005. doi: 10.1093/molbev/msg112. Epub 2003 Apr 25.
5
Cloning and comparative analysis of the bovine, porcine, and equine sex chromosome genes ZFX and ZFY.牛、猪和马的性染色体基因ZFX和ZFY的克隆及比较分析
Genome. 2004 Feb;47(1):74-83. doi: 10.1139/g03-099.
6
Comparison of ZFY and ZFX gene structure and analysis of alternative 3' untranslated regions of ZFY.ZFY与ZFX基因结构的比较及ZFY基因3'非翻译区可变区的分析
Nucleic Acids Res. 1991 May 25;19(10):2579-86. doi: 10.1093/nar/19.10.2579.
7
Evolution of zinc finger-Y and zinc finger-X genes in oryzomyne-akodontine rodents (Cricetidae).稻鼠亚科 - 南美原鼠亚科啮齿动物（仓鼠科）中锌指 - Y基因和锌指 - X基因的进化
J Mol Evol. 1992 Jan;34(1):54-61. doi: 10.1007/BF00163852.
8
CpG islands in human ZFX and ZFY and mouse Zfx genes: sequence similarities and methylation differences.人类ZFX和ZFY基因以及小鼠Zfx基因中的CpG岛：序列相似性与甲基化差异
Genomics. 1995 Sep 20;29(2):353-63. doi: 10.1006/geno.1995.9994.
9
Molecular evolution of the ZFY and ZNF6 gene families.ZFY 和 ZNF6 基因家族的分子进化
Mol Biol Evol. 1998 Feb;15(2):129-37. doi: 10.1093/oxfordjournals.molbev.a025909.
10
Cloning and mapping of bovine ZFX gene to the long arm of the X-chromosome (Xq34) and homologous mapping of ZFY gene to the distal region of the short arm of the bovine (Yp13), ovine (Yp12-p13), and caprine (Yp12-p13) Y chromosome.牛ZFX基因的克隆及定位至X染色体长臂（Xq34），以及牛（Yp13）、绵羊（Yp12 - p13）和山羊（Yp12 - p13）Y染色体短臂远端区域的ZFY基因同源定位。
Mamm Genome. 1998 Feb;9(2):125-30. doi: 10.1007/s003359900702.

引用本文的文献

1
Patterns of Y and X chromosome DNA sequence divergence during the Felidae radiation.猫科动物辐射演化过程中Y染色体和X染色体DNA序列的分歧模式。
Genetics. 1998 Mar;148(3):1245-55. doi: 10.1093/genetics/148.3.1245.
2
Male-biased distribution of the human Y chromosomal genes SRY and ZFY in the lizard Calotes versicolor, which lacks sex chromosomes and temperature-dependent sex determination.在变色树蜥（Calotes versicolor）中，人类Y染色体基因SRY和ZFY呈现出雄性偏向分布，该物种缺乏性染色体且性别由温度决定。
Chromosome Res. 1997 Sep;5(6):413-9. doi: 10.1023/a:1018452526903.
3
Analysis of mutation rates in the SMCY/SMCX genes shows that mammalian evolution is male driven.

本文引用的文献

1
Molecular evolution of mRNA: a method for estimating evolutionary rates of synonymous and amino acid substitutions from homologous nucleotide sequences and its application.信使核糖核酸的分子进化：一种从同源核苷酸序列估计同义替换和氨基酸替换进化速率的方法及其应用
J Mol Evol. 1980 Sep;16(1):23-36. doi: 10.1007/BF01732067.
2
The sex-determining region of the human Y chromosome encodes a finger protein.人类Y染色体的性别决定区域编码一种指蛋白。
Cell. 1987 Dec 24;51(6):1091-104. doi: 10.1016/0092-8674(87)90595-2.
3
Male-driven molecular evolution: a model and nucleotide sequence analysis.
对SMCY/SMCX基因的突变率分析表明，哺乳动物的进化是由雄性驱动的。
Mamm Genome. 1997 Feb;8(2):134-8. doi: 10.1007/s003359900372.
4
Potential problems in estimating the male-to-female mutation rate ratio from DNA sequence data.从DNA序列数据估计男性与女性突变率之比时的潜在问题。
J Mol Evol. 1993 Aug;37(2):160-6. doi: 10.1007/BF02407351.
5
Contrasting rates of nucleotide substitution in the X-linked and Y-linked zinc finger genes.X 连锁和 Y 连锁锌指基因中核苷酸替换率的对比
J Mol Evol. 1994 Dec;39(6):569-78. doi: 10.1007/BF00160402.
6
Interchromosomal gene conversion as a possible mechanism for explaining divergence patterns of ZFY-related genes.染色体间基因转换作为解释ZFY相关基因分歧模式的一种可能机制。
J Mol Evol. 1992 Aug;35(2):181-3. doi: 10.1007/BF00183228.
Cold Spring Harb Symp Quant Biol. 1987;52:863-7. doi: 10.1101/sqb.1987.052.01.094.
4
Sequences homologous to ZFY, a candidate human sex-determining gene, are autosomal in marsupials.与作为人类性别决定基因候选基因的ZFY同源的序列在有袋类动物中是常染色体的。
Nature. 1988;336(6201):780-3. doi: 10.1038/336780a0.
5
Mammalian ZFY sequences exist in reptiles regardless of sex-determining mechanism.
Science. 1988 Oct 28;242(4878):567-9. doi: 10.1126/science.3140382.
6
An improved method for directly sequencing PCR amplified material using dimethyl sulphoxide.一种使用二甲基亚砜对聚合酶链反应扩增产物进行直接测序的改进方法。
Nucleic Acids Res. 1989 Feb 11;17(3):1266. doi: 10.1093/nar/17.3.1266.
7
Genetic evidence that ZFY is not the testis-determining factor.ZFY不是睾丸决定因子的遗传学证据。
Nature. 1989;342(6252):937-9. doi: 10.1038/342937a0.
8
Mammalian sex determination: thumbs down for zinc finger?
Nature. 1989;342(6252):860-2. doi: 10.1038/342860a0.
9
Three-dimensional solution structure of a single zinc finger DNA-binding domain.单个锌指DNA结合结构域的三维溶液结构
Science. 1989 Aug 11;245(4918):635-7. doi: 10.1126/science.2503871.
10
ZFX has a gene structure similar to ZFY, the putative human sex determinant, and escapes X inactivation.ZFX具有与假定的人类性别决定基因ZFY相似的基因结构，并且逃避X染色体失活。
Cell. 1989 Jun 30;57(7):1247-58. doi: 10.1016/0092-8674(89)90061-5.