Pfister Anne, Zhang Guoqing, Zareno Jessica, Horwitz Alan F, Fraser Cassandra L
Department of Chemistry, University of Virginia, McCormick Road, Charlottesville, Virginia 22904, USA.
ACS Nano. 2008 Jun;2(6):1252-8. doi: 10.1021/nn7003525.
Difluoroboron dibenzoylmethane-polylactide, BF(2)dbmPLA, a biocompatible polymer-luminophore conjugate was fabricated as nanoparticles. Spherical particles <100 nm in size were generated via nanoprecipitation. Intense blue fluorescence, two-photon absorption, and long-lived room temperature phosphorescence (RTP) are retained in aqueous suspension. The nanoparticles were internalized by cells and visualized by fluorescence microscopy. Luminescent boron biomaterials show potential for imaging and sensing.
二氟硼二苯甲酰甲烷-聚乳酸(BF(2)dbmPLA),一种生物相容性聚合物-发光体共轭物被制备成纳米颗粒。通过纳米沉淀法生成了尺寸小于100纳米的球形颗粒。在水悬浮液中保留了强烈的蓝色荧光、双光子吸收和长寿命室温磷光(RTP)。纳米颗粒被细胞内化并通过荧光显微镜观察。发光硼生物材料在成像和传感方面显示出潜力。