Guan Xiao-Yang, Shi Min
State Key Laboratory of Organometallic Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, 354 Fenglin Lu, Shanghai, 200032, China.
Org Biomol Chem. 2008 Oct 7;6(19):3616-20. doi: 10.1039/b810299f. Epub 2008 Aug 4.
A three-component reaction of beta-nitrostyrene, arylmethylidenemalononitrile and malononitrile catalyzed by imidazole produced the corresponding polysubstituted cyclohexene derivatives in moderate to good yields under mild conditions. A further improvement of this three-component reaction has also been achieved by starting from a commercially available aromatic aldehyde, nitromethane and malononitrile to give the products in moderate yields.
由咪唑催化的β-硝基苯乙烯、芳基亚甲基丙二腈和丙二腈的三组分反应，在温和条件下以中等至良好的产率生成了相应的多取代环己烯衍生物。通过从市售的芳香醛、硝基甲烷和丙二腈开始反应，该三组分反应也得到了进一步改进，能以中等产率得到产物。
