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使用2%茶洗剂与5%硫酸锌溶液治疗寻常痤疮的局部疗法。

Topical therapy of acne vulgaris using 2% tea lotion in comparison with 5% zinc sulphate solution.

作者信息

Sharquie Khalifa E, Noaimi Adil A, Al-Salih Mazin M

机构信息

Department of Dermatology and Venereology, Iraqi Board for Medical Specializations, Medical Collection Office, Baghdad, Iraq.

出版信息

Saudi Med J. 2008 Dec;29(12):1757-61.

Abstract

OBJECTIVE

To evaluate effectiveness of 2% tea lotion in comparison with 5% zinc sulphate solution in the treatment of acne vulgaris.

METHODS

This is a single-blind randomly comparative therapeutic clinical trial carried out in the Department of Dermatology, Baghdad Teaching Hospital, Baghdad, Iraq from June 2006 to December 2007. Full history and clinical examination were studied for each patient regarding all relevant points of the disease, to evaluate the severity of acne. Forty-seven patients with acne vulgaris were divided randomly into 2 groups, and were instructed to use the following solutions twice daily for 2 months; group A used 2% tea lotion, group B used 5% zinc sulphate solution. Patients with papulopustular lesions were included in the study, while patients with severe acne were excluded. The clinical improvement was scored by counting the number of inflammatory lesions before, and after treatment.

RESULTS

Forty patients completed the study, their ages ranged from 13-27 years with a mean+/-standard deviation of 19.5+/-3.5 years with 20 patients in each group. Two percent tea lotion was statistically significant in decreasing the number of the inflammatory lesions in acne vulgaris, while 5% zinc sulphate solution was beneficial, but did not reach statistically significant level as tea lotion.

CONCLUSION

Two percent tea lotion was a good alternative remedy to be used in the treatment of acne vulgaris, and was much superior than topical 5% zinc sulphate solution.

摘要

目的

比较2%茶洗剂与5%硫酸锌溶液治疗寻常痤疮的疗效。

方法

这是一项单盲随机对照治疗性临床试验,于2006年6月至2007年12月在伊拉克巴格达巴格达教学医院皮肤科进行。对每位患者就该疾病的所有相关要点进行全面病史和临床检查,以评估痤疮的严重程度。47例寻常痤疮患者随机分为2组,指导其每天使用以下溶液两次,持续2个月;A组使用2%茶洗剂,B组使用5%硫酸锌溶液。纳入丘疹脓疱性皮损患者,排除重度痤疮患者。通过计算治疗前后炎症性皮损的数量对临床改善情况进行评分。

结果

40例患者完成研究,年龄在13 - 27岁之间,平均年龄±标准差为19.5±3.5岁,每组20例。2%茶洗剂在减少寻常痤疮炎症性皮损数量方面具有统计学意义,而5%硫酸锌溶液虽有效果,但未达到茶洗剂的统计学显著水平。

结论

2%茶洗剂是治疗寻常痤疮的一种良好替代疗法,且比外用5%硫酸锌溶液优越得多。

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