Beksaç Burak, Salas Antonio, González Della Valle Alejandro, Salvati Eduardo A
Department of Orthopedic Surgery, Hospital for Special Surgery, 535 East 70th Street, New York, NY 10021, USA.
Clin Orthop Relat Res. 2009 Jul;467(7):1765-72. doi: 10.1007/s11999-008-0661-1. Epub 2008 Dec 12.
Highly cross-linked polyethylene (HCLPE) has been used extensively to decrease osteolysis and related implant failure in THA. We compared the wear rate of HCLPE and noncross-linked conventional PE (CPE) liners and the rate of radiographic calcar resorption and osteolysis in young patients (35-60 years of age) who underwent THA by one surgeon. Thirty-four patients (41 THAs) who received a hybrid THA using a HCLPE liner were match-paired for age, gender, body mass index, and diagnosis with a group of patients who underwent THA with identical implants but with a CPE liner. The minimum followup was 4 years (average, 5.3; range, 4-8 years). Using the Livermore measurement technique, the averages of total wear of the HCLPE and CPE liners were 0.01 mm (range, -0.23-0.4) and 0.64 mm (range, 0-1.7), respectively. The average annual wear was less for the HCLPE than the noncross-linked PE (0.002 mm, range, -0.05-0.1 versus 0.12 mm, range, 0-0.29, respectively). Four hips in the HCLPE group and 23 in the CPE group had calcar resorption measuring averages of 2.5 mm (range, 2-3) and 7.5 mm (range, 1.8-23.8), respectively. Periprosthetic osteolysis occurred in two and eight hips in the HCLPE and CPE groups, respectively. Longer followup is needed to determine if these findings will result in improved implant survivorship.
Level III, therapeutic study.
高度交联聚乙烯(HCLPE)已被广泛用于减少全髋关节置换术(THA)中的骨溶解及相关植入物失败。我们比较了HCLPE和非交联传统聚乙烯(CPE)衬垫的磨损率,以及在由同一位外科医生进行THA的年轻患者(35至60岁)中影像学上股骨距吸收和骨溶解的发生率。34例接受使用HCLPE衬垫的混合THA的患者,在年龄、性别、体重指数和诊断方面与一组接受相同植入物但使用CPE衬垫进行THA的患者进行匹配配对。最短随访时间为4年(平均5.3年;范围4至8年)。使用利弗莫尔测量技术,HCLPE和CPE衬垫的总磨损平均值分别为0.01毫米(范围 -0.23至0.4)和0.64毫米(范围0至1.7)。HCLPE的年均磨损小于非交联聚乙烯(分别为0.002毫米,范围 -0.05至0.1,而0.12毫米,范围0至0.29)。HCLPE组有4例髋关节出现股骨距吸收,平均吸收量为2.5毫米(范围2至3),CPE组有23例,平均吸收量为7.5毫米(范围1.8至23.8)。HCLPE组和CPE组分别有2例和8例髋关节出现假体周围骨溶解。需要更长时间的随访来确定这些发现是否会改善植入物的生存率。
III级,治疗性研究。