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髋关节发育不良的非骨水泥型全髋关节置换术中交联聚乙烯或传统聚乙烯磨损与骨溶解分析的15年比较——一项回顾性队列研究

Fifteen-Year Comparison of Wear and Osteolysis Analysis for Cross-Linked or Conventional Polyethylene in Cementless Total Hip Arthroplasty for Hip Dysplasia-A Retrospective Cohort Study.

作者信息

Tsukamoto Manabu, Ohnishi Hideo, Mori Toshiharu, Kawasaki Makoto, Uchida Soshi, Sakai Akinori

机构信息

Department of Orthopaedic Surgery, School of Medicine, University of Occupational and Environmental Health, Kitakyushu, Japan.

Department of Orthopaedic Surgery, Moji Medical Center, Kitakyushu, Japan.

出版信息

J Arthroplasty. 2017 Jan;32(1):161-165.e1. doi: 10.1016/j.arth.2016.06.008. Epub 2016 Jun 23.

Abstract

BACKGROUND

Cross-linked polyethylene (XLPE) acetabular liners used in cementless total hip arthroplasty (THA) have demonstrated better wear resistance at 10 years compared with conventional polyethylene (CPE) liners. No clinical studies have compared XPLE to CPE liners beyond 10 years.

METHODS

We performed a 15-year retrospective cohort study on cementless THA performed in patients with developmental hip dysplasia to measure the differences in polyethylene wear rates and the presence of osteolysis. Twenty-four THAs with XLPE and 17 THAs with CPE were evaluated. The mean age of patients was 55.9 years (41-68) in the XLPE group and 54.4 years (40-67) in the CPE group. The mean follow-up period was 15.1 years (13.9-16.1) in the XLPE group and 15.2 years (14.5-16.0) in the CPE group.

RESULTS

The XLPE group had a significantly lower wear rate at 5 and 10 years compared with the CPE group; however, no significant difference was found at 15 years (XLPE group, 0.040 mm/y; CPE group, 0.034 mm/y). In addition, the incidence of osteolysis did not differ significantly between the groups. However, the incidence of excessive wear between 10 and 15 years after surgery in the XLPE group was significantly higher than that in the CPE group.

CONCLUSION

XLPE demonstrated no advantage in the wear rate or the incidence of osteolysis at 15 years, despite having superior wear resistance up to 10 years. It is concerning that the incidence of excessive wear was higher in the XLPE group between 10 and 15 years, and this finding should alert the arthroplasty community to this possible problem with the more highly cross-linked polyethylene.

摘要

背景

在非骨水泥型全髋关节置换术(THA)中使用的交联聚乙烯(XLPE)髋臼衬垫,与传统聚乙烯(CPE)衬垫相比,在10年时表现出更好的耐磨性。尚无临床研究对超过10年的XLPE和CPE衬垫进行比较。

方法

我们对发育性髋关节发育不良患者进行的非骨水泥型THA进行了一项为期15年的回顾性队列研究,以测量聚乙烯磨损率和骨溶解情况的差异。评估了24例使用XLPE的THA和17例使用CPE的THA。XLPE组患者的平均年龄为55.9岁(41 - 68岁),CPE组为54.4岁(40 - 67岁)。XLPE组的平均随访期为15.1年(13.9 - 16.1年),CPE组为15.2年(14.5 - 16.0年)。

结果

与CPE组相比,XLPE组在5年和10年时磨损率显著更低;然而,在15年时未发现显著差异(XLPE组,0.040 mm/年;CPE组,0.034 mm/年)。此外,两组之间骨溶解的发生率无显著差异。然而,XLPE组术后10至15年的过度磨损发生率显著高于CPE组。

结论

尽管XLPE在长达10年时具有卓越的耐磨性,但在15年时,其在磨损率或骨溶解发生率方面并无优势。令人担忧的是,XLPE组在10至15年期间过度磨损的发生率更高,这一发现应提醒关节置换学界关注这种高度交联聚乙烯可能存在的这一问题。

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